|
|
|
Low vitamin and carotenoid levels are related to cerebral white matter lesions
|
| submitted by tamfezz 5 months ago
|
|
To determine the effects of vitamins and carotenoids on brain white matter lesions (WMLs), we examined the associations between WMLs with vitamin and carotenoid levels in Japanese middle-aged and elderly subjects.Four-hundred and sixty-nine healthy participants (male = 317; female = 152) that underwent medical examinations were examined. Deep white matter lesions (DWLs) were detected via magnetic resonance imaging (MRI) in 39 subjects. We evaluated the effects of vitamin and carotenoid levels on DWLs via logistic regression analysis.Lower gamma-tocopherol levels were significantly associated with DWLs in all subjects. While lower gamma-tocopherol and vitamin C levels were significantly associated with DWLs in males, lower delta-tocopherol levels were associated with DWLs in females. The associations between DWLs and lower gamma- and delta-tocopherol and vitamin C levels were independent of age, hypertension, or smoking. However, the associations between DWLs and lower alfatocopherol were not significant following adjustments for smoking.Lower carotenoid and vitamin levels were independently associated with cerebral DWLs in Japanese subjects.
|
| Topic: Health |
|
Add your comment
Please Login or Signup to leave a comment
Related stories
|
|
| Function and neuroimaging in cerebral palsy: a population-based study |
| submitted by saghemarode 2 years and 1 month ago - Topic: Health |
|
The aim of this population-based study was to describe function in cerebral palsy (CP) in relation to neuroimaging.Method Motor function, accompanying impairments, and neuroimaging (86 by magnetic resonance imaging, 74 by computed tomography) were studied in 186 children born in western Sweden be...
|
|
|
|
| Histopathological correlates of MRI-Defined chronic perinatal white matter injury |
| submitted by sothyo 1 year and 11 months ago - Topic: Biology |
|
Although MRI is the optimal imaging modality to define cerebral white-matter injury (WMI) in preterm survivors, the histopathological features of MRI-defined chronic lesions are poorly defined. We hypothesized that chronic WMI is related to a combination of delayed oligodendrocyte (OL) lineage ce...
|
|
|
|
