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Biology |
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| Neurobiological insight into hyperbaric hyperoxia |
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submitted by spoz 1 hour ago - Topic: Biology |
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Hyperbaric hyperoxia (HBO) is known to modulate aerobic metabolism, vasoreactivity and blood flow in the brain. Nevertheless, mechanisms underlying its therapeutic effects, especially in traumatic brain injury (TBI) and stroke patients, are debated. The present study aimed at investigating region...
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| Glucose homeostasis in rats exposed to acute intermittent hypoxia |
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submitted by spoz 1 hour ago - Topic: Biology |
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Chronic exposure to intermittent hypoxia commonly induces the activation of sympathetic tonus and the disruption of glucose homeostasis. However the effects of exposure to acute intermittent hypoxia (AIH) on glucose homeostasis are not yet fully elucidated. Herein, we evaluated parameters related...
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| Hypoxia inducible factor signalling mechanisms in the central nervous system |
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submitted by spoz 1 hour ago - Topic: Biology |
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In the CNS neurons are highly sensitive to the availability of oxygen. In conditions where oxygen availability is decreased neuronal function can be altered, leading to injury and cell death. Hypoxia has been implicated in a number of central nervous system pathologies including stroke, head trau...
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| Brazilein suppresses migration and invasion of MDA-MB-231 breast cancer cells |
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submitted by 164276098 2 hours ago - Topic: Biology |
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Brazilein, a bioactive compound isolated from Caesalpinia sappan L., has long been used in oriental folk medicines. Cancer metastasis is a primary cause of cancer death. However, the anti-metastatic effects of brazilein remain elusive. In this study, we found that brazilein inhibited human breast...
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