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Personality and long-term reproductive success measured by the number of grandchildren
submitted by hetz2333 20 minutes ago - Topic: Biology
Personality, that is, individual behavioral tendencies that are relatively stable across situations and time, has been associated with number of offspring in many animals, including humans, suggesting that some personality traits may be under natural selection. However, there are no data on whether these associations between personality and reproductive success extend over more than one generat...



Mutualism and manipulation in Hadza-honeyguide interactions
submitted by hetz2333 20 minutes ago - Topic: Biology
We investigated the ecology and evolution of interspecific cooperation between the Greater Honeyguide bird, Indicator indicator, and human hunter-gatherers, the Hadza of northern Tanzania. We found that honeyguides increased the Hadza's rate of finding bee nests by 560%, and that the birds led men to significantly higher yielding nests than those found without honeyguides. We estimate that 8-10...

Someone to live for: effects of partner and dependent children on preventable death in a population wide sample from Northern Ireland
submitted by hetz2333 20 minutes ago - Topic: Biology
How to allocate resources between somatic maintenance and reproduction in a manner that maximizes inclusive fitness is a fundamental challenge for all organisms. Life history theory predicts that effort put into somatic maintenance (health) should vary with sex, mating and parenting status because men and women have different costs of reproduction, and because life transitions such as family fo...

Adalimumab monotherapy versus combination therapy with immunomodulators in patients with Crohn's disease: A systematic review and meta-analysis
submitted by sarish 24 minutes ago - Topic: Health
Combination therapy with infliximab and azathioprine has been shown to be superior to either treatment alone in Crohn's disease (CD). However, the benefit of combining adalimumab with an immunomodulator remains controversial. The aim of this study was to compare the efficacy of adalimumab monotherapy with combination therapy for induction and maintenance of response and remission in CD using a ...

Evaluation of glycogen storage disease as a cause of ketotic hypoglycemia in children
submitted by sothyo 1 hour ago - Topic: Health
Ketone formation is a normal response when hypoglycemia occurs. Since the majority of children with recurrent hypoglycemia cannot be diagnosed with a known endocrine or metabolic disorder on a critical sample, ketotic hypoglycemia has been described as the most common cause of low blood glucose concentrations in children. Critical samples, however, will miss the ketotic forms of glycogen storag...



Personalized medicine approaches for colon cancer driven by genomics and systems biology: OncoTrack
submitted by amor 1 hour ago - Topic: Biology
The post-genomic era promises to pave the way to a personalized understanding of disease processes, with technological and analytical advances helping to solve some of the world's health challenges. Despite extraordinary progress in our understanding of cancer pathogenesis, the disease remains one of the world's major medical problems. New therapies and diagnostic procedures to guide their clin...

Flow and geometry induced scattering of high frequency acoustic duct modes
submitted by prencib5mi 1 hour ago - Topic: Geography
Cut-on cut-off transition of acoustic modes in hard-walled ducts with irrotational mean flow is well understood for Helmholtz numbers of order unity. Previous finite-element simulations of this phenomenon, however, appear to indicate the possibility of energy scattering into neighbouring modes at moderately large Helmholtz numbers. In this paper, such scattering phenomena are explained and pred...


A model of acoustic absorption in fluids based on a continuous distribution of relaxation times
submitted by prencib5mi 1 hour ago - Topic: Geography
This work extends the quasi-equilibrium relaxation theory of sound absorption in liquids to the case of continuous distribution of relaxation times. Such extension is needed when absorption mechanisms are not confined to the action of viscosity and heat conduction, but are mainly due to the excitation of a large number of internal molecular degrees of freedom. In this case the conventional Navi...

Normal and abnormal development of the aortic wall and valve: correlation with clinical entities
submitted by mpeipir 1 hour ago - Topic: Health
Dilation of the wall of the thoracic aorta can be found in patients with a tricuspid (TAV) as well as a bicuspid aortic valve (BAV) with and without a syndromic component. BAV is the most common congenital cardiovascular malformation, with a population prevalence of 0.5–2 %. The clinical course is often characterised by aneurysm formation and in some cases dissection. The non-dilated aortic ...


Agrobacterium-mediated high-frequency transformation of an elite commercial maize (Zea mays L.) inbred line
submitted by goremo 1 hour ago - Topic: Biology
An improvedAgrobacterium-mediated transformation protocol is described for a recalcitrant commercial maize elite inbred with optimized media modifications and AGLThese improvements can be applied to other commercial inbreds. This study describes a significantly improved Agrobacterium-mediated transformation protocol in a recalcitrant commercial maize elite inbred, PHR03, using optimal co-cultiv...

Overexpression of Camellia sinensis H1 histone gene confers abiotic stress tolerance in transgenic tobacco
submitted by goremo 1 hour ago - Topic: Biology
Overexpression ofCsHisin tobacco promoted chromatin condensation, but did not affect the phenotype. It also conferred tolerance to low-temperature, high-salinity, ABA, drought and oxidative stress in transgenic tobacco. H1 histone, as a major structural protein of higher-order chromatin, is associated with stress responses in plants. Here, we describe the functions of the Camellia sinensis H1 H...


The abiotic stress-responsive NAC-type transcription factor SlNAC4 regulates salt and drought tolerance and stress-related genes in tomato (Solanum lycopersicum)
submitted by goremo 1 hour ago - Topic: Biology
SlNAC4 functions as a stress-responsive transcription factor and might be useful for crop salt and drought tolerance improvement. Abiotic stresses, especially salinity and drought, are major factors that significantly limit crop growth and productivity. Plant-specific NAC transcription factors play crucial roles in various stress responses. However, to date only little information regarding str...

Fine mapping and candidate gene analysis of a major QTL for panicle structure in rice
submitted by goremo 1 hour ago - Topic: Biology
A gene not only control tiller and plant height, but also regulate panicle structure by QTL dissection in rice. An ideal panicle structure is important for improvement of plant architecture and rice yield. In this study, using recombinant inbred lines (RILs) of PA64s and 93-11, we identified a quantitative trait locus (QTL), designated qPPB3 for primary panicle branch number. With a BC3F2 popul...

Neuroimaging craving: urge intensity matters
submitted by foizihkofe 1 hour ago - Topic: Health
Functional neuroimaging has become an increasingly common tool for studying drug craving. Furthermore, functional neuroimaging studies, which have addressed an incredibly diverse array of questions regarding the nature and treatment of craving, have had a substantial impact on theoretical models of addiction. Here, we offer three points related to this sizeable and influential body of research....

The Forest and the Trees: Relational and Specific Factors in Addiction Treatment
submitted by foizihkofe 1 hour ago - Topic: Health
Increased expectations for the use of evidence-based methods in addiction treatment have fueled a debate regarding the relative importance of “specific” versus “common” factors in treatment outcome. This review explores the influence of these factors on addiction treatment outcome. The authors review and link findings from four decades of research on specific and general factors in addi...