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Yeast synthetic biology for high-value metabolites
submitted by foizihkofe 1 minute ago - Topic: Biology
Traditionally, high-value metabolites have been produced through direct extraction from natural biological sources which are inefficient, given the low abundance of these compounds. On the other hand, these high-value metabolites are usually difficult to be synthesized chemically, due to their complex structures. In the last few years, the discovery of genes involved in the synthetic pathways o...



The synthetic biology toolbox for tuning gene expression in yeast
submitted by foizihkofe 1 minute ago - Topic: Biology
Saccharomyces cerevisiae can serve as a key production platform for biofuels, nutraceuticals, industrial compounds, and therapeutic proteins. Over the recent years, synthetic biology tools and libraries have expanded in yeast to provide newfound control over regulation and synthetic circuits. This review provides an update on the status of the synthetic biology toolbox in yeast for use as a cel...

Mathematical Aspects for RNSS Constellation with IGSO Satellites
submitted by sarish 3 minutes ago - Topic: Geography
Besides from existing global navigation satellite system (GNSS), several countries such as France, Indian, Japan and China have being developing their regional navigation satellite system (RNSS) in recent years. The Inclined Geosynchronous Orbit (IGSO) satellites with a big inclination angle play an important role in these RNSS constellations. The mathematical aspects of RNSS constellations are...

The impact of the hospital work environment on social support from physicians in breast cancer care
submitted by aldtemigomeng 4 minutes ago - Topic: Health
Research on determinants of a good patient-physician interaction mainly disregards systemic factors, such as the work environment in healthcare. This study aims to identify stressors and resources within the work environment of hospital physicians that enable or hinder the physicians’ provision of social support to patients. Four data sources on 35 German breast cancer center hospitals were m...

Confusion in and about shared decision making in hospital outpatient encounters
submitted by aldtemigomeng 4 minutes ago - Topic: Health
To explore how physician efforts to involve patients in medical decisions align with established core elements of shared decision making (SDM). Detailed video analysis of two hospital outpatient encounters, selected because the physicians exhibited much effort to involve the patients in decision making, and because the final decisions were not what the physicians had initially recommended. The ...



Understanding patient perceptions of shared decision making
submitted by aldtemigomeng 4 minutes ago - Topic: Health
This study aims to develop a conceptual model of patient-defined SDM, and understand what leads patients to label a specific, decision-making process as shared. Qualitative interviews were conducted with 23 primary care patients following a recent appointment. Patients were asked about the meaning of SDM and about specific decisions that they labeled as shared. Interviews were coded using quali...

Health literacy, alcohol expectancies, and alcohol use behaviors in teens
submitted by aldtemigomeng 4 minutes ago - Topic: Health
Alcohol expectancies are developed, in part, through exposure to health messages, the understanding of which may be influenced by health literacy. This study explores the relationships among health literacy, alcohol expectancies, and alcohol use behaviors in teens. We studied alcohol use behaviors in the past six months in youths aged 14-19 recruited from two adolescent medicine clinics. We ass...


What Are Internal Medicine Residents Missing? A communication needs assessment of outpatient clinical encounters
submitted by aldtemigomeng 4 minutes ago - Topic: Health
In order to guide curricular innovation, we looked at the feasibility and utility of performing a targeted needs assessment of the communication skills of PGY2 internal medicine (IM) residents in their continuity clinic, utilizing faculty direct observation with a validated instrument for communication skills evaluation. A convenience sample of PGY2 residents in the Emory University School of M...

Cross-cultural adaptation and validation of the health literacy assessment tool METER in the Portuguese adult population
submitted by aldtemigomeng 4 minutes ago - Topic: Health
We aimed to culturally adapt and validate METER in the Portuguese population, and to define cut-off values for adequate health literacy. We used the standard procedure for the adaptation of the words and surveyed health professionals to select the non-words. The instrument was administered to a total sample of 249 participants and retested in a sub-sample of 45 after three months. Cut-offs were...


Applying the Verona Coding Definitions of Emotional Sequences (VR-CoDES) in the dental context involving patients with complex communication needs: an exploratory study
submitted by aldtemigomeng 4 minutes ago - Topic: Health
The VR-CoDES has been previously applied in the dental context. However, we know little about how dental patients with intellectual disabilities (ID) and complex communication needs express their emotional distress during dental visits. This is the first study explored the applicability of the VR-CoDES to a dental context involving patients with ID. Fourteen dental consultations were video reco...

Examining patients’ trust in physicians and the VA healthcare system in a prospective cohort followed for six-months after an exacerbation of heart failure
submitted by aldtemigomeng 4 minutes ago - Topic: Health
To examine the associations of several characteristics with patients’ trust in physician and the healthcare system. A prospective cohort of patients were followed after an exacerbation of heart failure at one of two Veterans Affairs (VA) hospitals. Patients rated pre-visit and post-visit trust in physician and in the VA healthcare system at follow-up outpatient visits. The associations of tru...


Physicians’ Influence on Veterans’ Decision to Use Acupuncture
submitted by aldtemigomeng 4 minutes ago - Topic: Health
To compare patients’ acupuncture use with physician's attitudes towards and history of referral for acupuncture. A questionnaire was administered to patients of the Atlanta Veterans Affairs Medical Center and the physicians whom they identified as most influencing their healthcare decisions. A total of 114 patients were matched with 33 physicians. Physicians’ history of referral was not sig...

What to listen for in the first consultation. Breast cancer patients’ own focus on talking about acceptance-based psychological coping predicts decreased psychological distress and depression
submitted by aldtemigomeng 4 minutes ago - Topic: Health
To analyze whether qualitative themes in breast cancer patients’ self-presentations predicted symptoms of psychological distress and depression in order to improve the consultation process. 97 breast cancer patients gave unstructured, 10-minute self-presentations at their first consultation in a clinical registered trial (CRT identifier: NCT00990977). Self-presentations were categorized thema...

Gestures convey content: An exploration of the semantic functions of physicians’ gestures
submitted by aldtemigomeng 4 minutes ago - Topic: Health
Gestures’ semiotic role in clinical interactions is unexplored. Using theoretical underpinnings from basic research on gesture, our objective was to investigate the semantic contributions of physicians’ gestures during interactions with patients with a different native language. We analyzed gestures-speech composites in eight videotaped interactions between physicians and patients during tr...

Hematologic differences between Dachshunds and mixed breed dogs
submitted by safeo 7 minutes ago - Topic: Agriculture
Healthy Dachshunds, like Greyhounds, are reported to have a higher HCT than other dog breeds; however, there appears to be no objective information to support this observation. The purpose of this study was to determine whether RBC counts, indices, and total and differential WBC counts differ between Dachshunds and mixed breed dogs. In this retrospective study, CBC data and total solids were co...