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Influence of a novel electrocardiogram-synchronized rotational-speed-change system of an implantable continuous-flow left ventricular assist device (EVAHEART) on hemolytic performance
submitted by vencieadeco 22 minutes ago - Topic: Health
We developed a novel controller for a continuous-flow left ventricular assist device (EVAHEART) that can change the pump’s rotational speed (RS) in synchronization with a patient’s myocardial electrocardiogram (ECG) with the aim of facilitating cardiac recovery. We previously presented various applications of this system in animal models, but there remained a concern that the repeated accel...



Impfungen in der frauenärztlichen Praxis – Teil 2
submitted by efonofla 26 minutes ago - Topic: Health
Mit besonderer Fokussierung auf für die gynäkologische und geburtshilfliche Praxis relevante Aspekte werden impfpräventable Erkrankungen detailliert und mit Impfindikationen dargestellt, genannt werden ebenfalls die für die Abrechnung notwendigen Abrechnungsnummern. Damit lassen sich Impfungen in die tägliche Praxisarbeit implementieren. Den dem Frauenarzt anvertrauten Patientinnen kann zu...

Examining the Mediating Roles of Microblog Use in the Relationships between Narcissism, Social Anxiety, and Social Capital
submitted by poddeikeoa 27 minutes ago - Topic: Health
Microblog is a platform for publishing and sharing short (140 characters or less) messages with others within a user's social network – is an Internet medium that is growing exponentially and changing the way people communicate on the Internet. To explore the effect of microblogging on interpersonal relationships, this study examines the relationships between narcissism, social anxiety, and m...

The Structure and Characteristics of Adolescents' Motivation in Micro-Blog Use
submitted by poddeikeoa 27 minutes ago - Topic: Health
The present study aims to clarify the structure of adolescents' motivations in micro-blog use and develop the corresponding scale. The results show that: (1) Adolescents' motivation in using micro-blog contains 14 items which can be classified into four dimensions, namely Show-Extrication, Convenience-Communication, Information-Sociality, and Leisure-Expression. The scale is of good reliability...

Japanese Deaf Adolescents' Textisms
submitted by poddeikeoa 27 minutes ago - Topic: Health
This study investigated how texting was used by deaf adolescents in Japan. A small corpus of dyadic messages exchanged via cell phone between 2 deaf high-school students at a residential school was collected to examine the features of unconventional spellings typically used in text messages, or “textisms.” The characteristics of this text-message corpus were analyzed along with the factors ...



A Qualitative Analysis of Online Gaming
submitted by poddeikeoa 27 minutes ago - Topic: Health
The popularity of Massively Multi-Player Online Role-Playing Games (MMORPGs) has risen dramatically over the last decade. Some gamers spend many hours a day in these virtual environments interacting with other gamers, completing quests, and forming social groups. The present study set out to explore the experiences and feelings of online gamers. The study comprised 71 interviews with online gam...

Disclosure and Privacy Settings on Social Networking Sites
submitted by poddeikeoa 27 minutes ago - Topic: Health
The present study evaluated a video-based intervention designed to permit users of social networking to make informed decisions about the information they disclosed online. The videos provided information regarding potential risks of disclosure and well as step-by-step instructions on privacy setting use. Novice (n=40) and experienced (n=40). FacebookTM users were randomly assigned to either th...


MRI screening of women with hereditary predisposition to breast cancer: diagnostic performance and survival analysis
submitted by wonnybanny 28 minutes ago - Topic: Health
Mri screening has been shown to allow for an earlier diagnosis of breast cancer in asymptomatic women with proven or suspected mutations in breast cancer susceptibility genes. Major efforts are presently addressed to assess to which extent this improves high-risk women survival. We here discuss the article by Gareth et al (Breast Cancer Res Treat 145:663–672, 2014). Gareth and colleagues comp...

AR collaborates with ERα in aromatase inhibitor-resistant breast cancer
submitted by wonnybanny 28 minutes ago - Topic: Health
Androgen receptor (AR) is an attractive target in breast cancer because of its frequent expression in all the molecular subtypes, especially in estrogen receptor (ER)-positive luminal breast cancers. We have previously shown a role for AR overexpression in tamoxifen resistance. We engineered ER-positive MCF-7 cells to overexpress aromatase and AR (MCF-7 AR Arom cells) to explore the role of AR ...


Assessment of Intraoperative Blood Loss during Oral and Maxillofacial Surgical Procedures in a Nigerian Tertiary Health Care Center
submitted by stippigald 28 minutes ago - Topic: Health
Reports on estimated amount of blood loss in maxillofacial surgical procedures will guide clinicians through units of blood required for each procedure. The aim of the study was to assess the amount of blood loss and duration of surgery. Methods. All cases of maxillofacial surgical procedures done under GA in the MFU theatre, from January 2007 to December 2013, were included in the study. Pre- ...

Pharmacokinetics, Pharmacodynamics, and Tolerability of Single Ascending Doses of RCT-18 in Chinese Patients with Rheumatoid Arthritis
submitted by corlahomilenck 29 minutes ago - Topic: Health
RCT-18 is a novel recombinant fusion protein that targets and neutralizes B-lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL). This first in-human study investigated the safety, tolerability, pharmacokinetics, immunogenicity, and pharmacodynamics of RCT-18 in patients with rheumatoid arthritis (RA). This was a single-center, randomized, single-blind, placebo-controlled st...


A Review of the Pharmacological Properties of Insulin Degludec and Their Clinical Relevance
submitted by corlahomilenck 29 minutes ago - Topic: Health
Insulin degludec (IDeg) is a new-generation basal insulin with an ultra-long duration of action. To date, a large number of studies have been conducted to investigate the pharmacokinetic and pharmacodynamic properties of IDeg. Standardised methods for collection and analysis of blood samples (for pharmacokinetic endpoints) and euglycaemic clamp procedures (for pharmacodynamic endpoints) were ap...

The levels of anti-HPV16/18 and anti-HPV31/33/35/45/52/58 antibodies among AS04-adjuvanted HPV16/18 vaccinated and non-vaccinated Ugandan girls aged 10-16 years
submitted by prikaenyon 30 minutes ago - Topic: Health
Data on Human Papilloma virus (HPV) vaccine immune response in sub-Saharan Africa is still sparse yet such knowledge is critical for optimal implementation and monitoring of HPV vaccines. Our primary objective was to evaluate levels of anti-HPV-16/18 antibodies and six other 'high risk' HPV (hrHPV) types among the vaccinated and unvaccinated Ugandan girls. We conducted a cross sectional study a...

Phylogeny of genera Laminaria and Saccharina (Laminariales, Phaeophyceae) based on three molecular markers
submitted by bshodi 30 minutes ago - Topic: Geography
In the past two decades, many studies have focused on the classification within genus Laminaria, ultimately trying to divide it into two subgroups or genera: Laminaria and Saccharina. A significant debate still surrounds the question of its division, as the conflicting phylogenetic hypotheses that have resulted from the classification studies are based on different taxon sampling, molecular mar...

Research on data pre-deployment in information service flow of digital ocean cloud computing
submitted by bshodi 30 minutes ago - Topic: Geography
Data pre-deployment in the HDFS (Hadoop distributed file systems) is more complicated than that in traditional file systems. There are many key issues need to be addressed, such as determining the target location of the data prefetching, the amount of data to be prefetched, the balance between data prefetching services and normal data accesses. ing to solve these problems, we employ the charact...