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Risk stratification and rapid geriatric screening in an emergency department - a quasi-randomised controlled trial
submitted by shohed 13 minutes ago - Topic: Health
To determine if risk stratification followed by rapid geriatric screening in an emergency department (ED) reduced functional decline, ED reattendance and hospitalisation. MethodThis was a quasi-randomised controlled trial. Patients were randomised by the last digit of their national registration identity card (NRIC). Odd number controls received standard ED care; even number patients received g...



The qualitative risk assessment of MINI, MIDI and MAXI horizontal directional drilling projects
submitted by egbamog 18 minutes ago - Topic: Geography
The differences between uncertainty, risk and hazard in horizontal directional drilling (HDD) technology were described in this paper. Various types of uncertainty in HDD technology were shown on the chosen examples. Due to the increasing complexity of HDD projects, the continuous development in HDD technology, the optional possibility of applying various tools and machines and the diversity in...

Met-CCL5 represents an immunotherapy strategy to ameliorate rabies virus infection
submitted by mockinta 19 minutes ago - Topic: Health
Infection of rabies virus (RABV) causes central nervous system (CNS) dysfunction and results in high mortality in human and animals. However, it is still unclear whether and how CNS inflammation and immune response contribute to RABV infection. Suckling mice were intracerebrally infected with attenuated RABV aG and CTN strains, followed by examination of chemokine or cytokine production, inflam...

Expression of 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) and its roles in activated microglia in vivo and in vitro
submitted by mockinta 19 minutes ago - Topic: Health
We reported previously that amoeboid microglial cells in the postnatal rat brain expressed 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) both in vivo and in vitro; however, the functional role of CNPase in microglia has remained uncertain. This study extended the investigation to determine CNPase expression in activated microglia derived from cell culture and animal models of brai...

Effects of mangrove structure on fish distribution patterns and predation risks
submitted by mclezodo 20 minutes ago - Topic: Biology
This study examined the effects of mangrove structure on fish distribution patterns and predation risks in southern Japan, utilizing field experiments in which artificial units mimicked mangrove root structure and canopy shade in a mangrove estuary. Fishes responded strongly to the different levels of root structure complexity but not to canopy shade, fish species richness and abundance being c...



Holothuria tubulosa Gmelin 1791 (Holothuroidea, Echinodermata) enhances organic matter recycling in Posidonia oceanica meadows
submitted by mclezodo 20 minutes ago - Topic: Biology
The role of Holothuria tubulosa in organic matter recycling of Posidonia oceanica detritus was estimated in a laboratory feeding experiment. The individual mean ingestion rate of seagrass detritus by holothurians was evaluated and carbon and nitrogen stable isotopes, carbon and nitrogen content and C:N ratio analyzed in H. tubulosa, P. oceanica detritus and surface sediment. showed that H. tubu...

Temporary rivers: linking ecohydrology, ecological quality and reconciliation ecology
submitted by jenx 20 minutes ago - Topic: Geography
Temporary streams and rivers, also referred to as intermittent, are defined as waterways that cease to flow at some points in space and time along their course. They are shaped by alternating wet and dry periods over annual and inter-annual cycles, making them one of the most dynamic freshwater ecosystems. These distinctive systems represent a substantial proportion of the total number, length ...


Fate, transport and effects of pollutants originating from acid mine drainage in the olifants river, south africa
submitted by jenx 20 minutes ago - Topic: Geography
Concentrations of pollutants were measured in water, sediment and algal samples collected along a longitudinal gradient from a stretch of the Olifants River, South Africa, that receives acid mine drainage (AMD) from the Klipspruit River. The effects of AMD were determined through macroinvertebrate biotic indices (SASS5) and multivariate analysis of macroinvertebrate communities. The acidic Klip...

Life-history plasticity of riparian annual plants adapted to extreme variations in water level: mesocosm experiments
submitted by jenx 20 minutes ago - Topic: Geography
The riparian zones of reservoirs associated with regulated rivers in China experience annual fluctuations in water level of up to 30 m that may vary in timing from year to year. Few plant species can tolerate such hydrological perturbation, but short-lived riparian annuals might be evolutionarily pre-adapted to such conditions. This study investigated plasticity of life history in four annual...


Antibody Drug Conjugation: Future of Cancer Care
submitted by kinwelkens 21 minutes ago - Topic: Health
Antibody drug conjugates (ADCs) is an emerging class of Biotherapeutics which represents a unique treatment strategy in the field of Oncology. The majority of anticancer agents developed to date have substantial side effect profiles and a narrow therapeutic index. Antibody-drug conjugates (ADCs) combine the specificity of monoclonal antibodies (mAbs) with the potency of cytotoxic molecules, thu...

Aerosols –A Concern for Dentists
submitted by kinwelkens 21 minutes ago - Topic: Health
Aerosols and splatter produced during many dental procedures are a potential source of transmission of various diseases to dentist in a dental clinic. Aerosols are solid or liquid particles suspended in air with a diameter of less than 50 μm and airborne particles larger than 50 μm size are called as splatter. Microbial aerosols and splatter are generated during the use of high speed handpiec...


Bacterial Pneumonia
submitted by kinwelkens 21 minutes ago - Topic: Health
Pneumonia is an infection caused by microbial agents. Our respiratory system is colonized with commensal bacteria and it is continuously exposed to a variety of bacteria. It is very difficult in most of the cases to identify the causative microorganism and for the diagnosis of bacterial pneumonia. The signs and symptoms, diagnosis and treatment plans are discussed. Prognosis has been studied po...

Granulation Technology: Current Status and Recent Advances
submitted by kinwelkens 21 minutes ago - Topic: Health
Granulation is performed to a powder or mixture of powder in order to improve flow, uniformity of contents and increasing the compressibility etc. In present review article we summarized the latest developments in granulation technologies behind most commonly used granulation process. Article deals basic information along with advantages and disadvantages of various granulation methods. Granula...

Rapid RP-HPLC Method for Quantitative Determination of Emtricitabine in Bulk and Pharmaceutical Dosage Form
submitted by kinwelkens 21 minutes ago - Topic: Health
A simple, rapid, sensitive, linear, precise, accurate, rugged and robust RP-HPLC-PDA method was developed and validated for the determination of emtricitabine in bulk and capsule dosage form. Reversed-phase chromatography was performed on BDS hypersil C-18 (250 mm × 4.6 mm, 5 μm) column of Waters HPLC with Empower software. Methanol: water: acetonitrile 80:13.5:6.5 (v/v/v) was used as mobile ...

Phytoremediation of TNT in Soil at Vellore District, Tamilnadu, India
submitted by kinwelkens 21 minutes ago - Topic: Health
Phytoremediation, a relatively new technology of remediating the contaminated environment using plants and serves as a green technology with environmental friendly approach. The main aim of the current study is to carryout phytoremediation of organic compounds and toxic chemicals such as 2,4,6-trinitrotoluene (TNT). The removal of TNT in soil was carried out using the plant Hibiscus arnottianus...