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Frailty prevalence and slow walking speed in persons age 65 and older: implications for primary care
submitted by shohraaz 11 minutes ago - Topic: Health
Frailty in the elderly increases their vulnerability and leads to a greater risk of adverse events. According to various studies, the prevalence of the frailty syndrome in persons age 65 and over ranges between 3% and 37%, depending on age and sex. Walking speed in itself is considered a simple i...



A Fluorogenic TMP-Tag for High Signal-to-Background Intracellular Live Cell Imaging
submitted by kothylc234 11 minutes ago - Topic: Biology
Developed to complement the use of fluorescent proteins in live cell imaging, chemical tags enjoy the benefit of modular incorporation of organic fluorophores, opening the possibility of high photon output and special photophysical properties. However, the theoretical challenge in using chemical ...

Expansion of the Analytical Window for Oil Spill Characterization by Ultrahigh Resolution Mass Spectrometry: Beyond Gas Chromatography
submitted by tetas2095 12 minutes ago - Topic: Environment
Traditional tools for routine environmental analysis and forensic chemistry of petroleum have relied almost exclusively on gas chromatography–mass spectrometry (GC-MS), although many compounds in crude oil (and its transformation products) are not chromatographically separated or amenable to GC...

Transformation of 17α-Estradiol, 17β-Estradiol, and Estrone in Sediments Under Nitrate- and Sulfate-Reducing Conditions
submitted by tetas2095 12 minutes ago - Topic: Environment
The natural manure-borne hormones, 17α-estradiol (17α-E2), 17β-estradiol (17β-E2), and estrone (E1), are routinely detected in surface water near agricultural land and wastewater treatment facilities. Once in the stream network, hormones may enter the sediment bed where they are subject to an...

Insight into the Effects of Biochar on Manure Composting: Evidence Supporting the Relationship between N2O Emission and Denitrifying Community
submitted by tetas2095 12 minutes ago - Topic: Environment
Although nitrous oxide (N2O) emissions from composting contribute to the accelerated greenhouse effect, it is difficult to implement practical methods to mitigate these emissions. In this study, the effects of biochar amendment during pig manure composting were investigated to evaluate the inter-...



Copper-Induced Deregulation of microRNA Expression in the Zebrafish Olfactory System
submitted by tetas2095 12 minutes ago - Topic: Environment
Although environmental trace metals, such as copper (Cu), can disrupt normal olfactory function in fish, the underlying molecular mechanisms of metal-induced olfactory injury have not been elucidated. Current research has suggested the involvement of epigenetic modifications. To address this hypo...

Life Cycle Assessment of Hemp Cultivation and Use of Hemp-Based Thermal Insulator Materials in Buildings
submitted by tetas2095 12 minutes ago - Topic: Environment
The aim of this research is to assess the sustainability of a natural fiber, such as hemp (Cannabis sativa), and its use as thermal insulator for building applications. The sustainability of hemp was quantified by life cycle assessment (LCA) and particular attention was given to the amount of CO2...

Life in the “Plastisphere”: Microbial Communities on Plastic Marine Debris
submitted by tetas2095 12 minutes ago - Topic: Environment
Plastics are the most abundant form of marine debris, with global production rising and documented impacts in some marine environments, but the influence of plastic on open ocean ecosystems is poorly understood, particularly for microbial communities. Plastic marine debris (PMD) collected at mult...

The impact of mulch type on soil organic carbon and nitrogen pools in a sloping site
submitted by omanca 12 minutes ago - Topic: Agriculture
Three mulch treatments were tested for their ability to control erosion on a sloping site. Additionally, the choice of mulch can also enhance revegetation success and improve soil organic matter input. This study aimed to investigate the effects of three mulching treatments, hydro-seeding, granit...

Bacterial diversity of a wooded riparian strip soil specifically designed for enhancing the denitrification process
submitted by omanca 12 minutes ago - Topic: Agriculture
This research is part of a project aimed at verifying the potential of a specifically assessed wooded riparian zone in removing the excess of combined nitrogen from the Zero River so as to reduce nutrient inputs into the Venice Lagoon. Among the specific objectives of the project, there was the d...

Embrace, a model for integrated elderly care: study protocol of a randomized controlled trial on the effectiveness regarding patient outcomes, service use, costs, and quality of care
submitted by shohed 14 minutes ago - Topic: Health
Ongoing growth in health care expenditures and changing patterns in the demand for health care challenge societies worldwide. The Chronic Care Model (CCM), combined with classification for care needs based on Kaiser Permanente (KP) Triangle, may offer a suitable framework for change. The aim of t...

Development of a sandwich ELISA for quantifying hepcidin in Rainbow trout
submitted by welsani 17 minutes ago - Topic: Biology
One of the most widespread antimicrobial peptides (AMPs) in fish is the hepcidins, which have potent, broad-spectrum activity against viruses, bacteria, fungi, and parasites. Moreover, they play the role of central regulation of iron metabolism and their expression is over-regulated by bacterial ...

Calreticulin is a microbial-binding molecule with phagocytosis-enhancing capacity
submitted by welsani 17 minutes ago - Topic: Biology
Calreticulin (CRT) is a highly conserved calcium-binding protein mainly involved in directing proper conformation of proteins and controlling calcium level. Accumulating data also show that CRT is emerging as an immune-relevant molecule. In this study, we demonstrated that the CRT gene from the a...

A galectin from roughskin sculpin, Trachidermus fasciatus: Molecular cloning and characterization
submitted by welsani 17 minutes ago - Topic: Biology
Galectins are a family of β-galactoside-binding lectins, which have been proved to be involved in host-pathogen interactions by recognizing pathogen associated molecular patterns (PAMPs) on the surface of virus, bacteria, fungi and protozoa. In this study, a galactoside-binding lectin homologue ...

Characterization of MMP-9 gene from grass carp (Ctenopharyngodon idella): An Aeromonas hydrophila-inducible factor in grass carp immune system
submitted by welsani 17 minutes ago - Topic: Biology
Matrix metalloproteinase-9 (MMP-9) belongs to a family of zinc-dependent endopeptidases and is associated with vital inflammatory processes. Here, we isolated and characterized MMP-9 cDNA from grass carp (Ctenopharyngodon idella) (designated as CiMMP-9). The cDNA was 2,880 bp long and encoded a p...