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Place branding and economic development at the local level in Ontario, Canada
submitted by libareas 2 hours ago - Topic: Geography
Municipalities in Ontario, Canada are increasingly adopting place branding as a policy strategy, to promote economic development—that is, to attract investment, tourists, labour force, and residents. This study examines the extent of branding in the province of Ontario, Canada, through a comprehensive content analysis of municipal branding as presented through logos and slogans. This analysis...



Foucault, sustainable tourism, and relationships with the environment (human and nonhuman)
submitted by libareas 2 hours ago - Topic: Geography
Drawing on contemporary research into ethical consumption and sustainable tourism this article starts by outlining the ways in which sustainable tourism (and other forms of ethical consumption) has been understood as a means to perform class based distinctions. At this stage, it is suggested that whilst class may be one factor in understanding such a complex phenomena there might also be a need...

NDM-1-producing Enterobacteriaceae from South Africa: moving towards endemicity?
submitted by beggybaanty 2 hours ago - Topic: Biology
We describe four patients infected with NDM-1 Enterobacter cloacae, Citrobacter freundii and Serratia marcescens from South Africa that co-produced SHV-12, CTX-M-3, −15, were positive for qnrS, qnrA, aac(6’)-Ib-cr, rmtF, rmtC, and armA. Plasmids belonged to IncN, IncA/C replicon types with ccdAB and vagC/D addiction factors. Local and imported cases of NDM-producing bacteria co-exist within...

Language Aptitude and Long-term Achievement in Early Childhood L2 Learners
submitted by biishiqaaeo 2 hours ago - Topic: Health
Language aptitude comprises cognitive and perceptual abilities that predispose individuals to learn well or rapidly (Carroll 1981; Doughty et al. 2007) and that can interplay with age by moderating its effects on learning outcomes. Although there is agreement regarding the importance of aptitude, findings have been mixed regarding its role in child second language acquisition (e.g. Abrahamsson ...

An ignored cause of inflammation in patients undergoing continuous ambulatory peritoneal dialysis: periodontal problems
submitted by onceint3434 2 hours ago - Topic: Health
We aimed to assess whether there is a significant relation between periodontal health status and inflammation in uremic patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and also to reveal the efficiency of periodontal treatment in patients with various degrees of periodontal problems. Overall, 68 patients undergoing CAPD were included in the study. Clinical indices and measu...



Stoffwechselerkrankungen des Erwachsenen und Epilepsie
submitted by rochilt4ak 2 hours ago - Topic: Health
Stoffwechselerkrankungen (STWE) mit Epilepsie sind entweder erworben oder hereditär. Hereditäre STWE mit Epilepsie sind bei Erwachsenen selten. Die häufigsten STWE des Erwachsenen mit Epilepsie sind die mitochondrialen Erkrankungen. Die Epilepsie ist selten die dominante oder einzige klinische Manifestation des Phänotyps. Alle Typen von Anfällen kommen bei STWE mit Epilepsie vor, am häufi...

Construction of a citrus framework genetic map anchored by 708 gene-based markers
submitted by makhlismaarod 2 hours ago - Topic: Forestry
We developed 708 gene-based markers for citrus genome analysis. Sequence-tagged site (STS) primers were designed that were located in conserved exon regions and whose PCR products spanned genomic introns. Of these, 79.7 % comprised cleaved amplified polymorphic sequence markers. The gene-based markers and their annotation and position on Clementine scaffolds ver. 1.0 permitted comparison of th...


Genome size variation in the Fagaceae and its implications for trees
submitted by makhlismaarod 2 hours ago - Topic: Forestry
Polyploidization is a major source of diversification among plants, particularly during cladogenesis, but most evidence involves herbaceous temperate species. The prevalence of polyploidy among woody taxa is largely unknown, especially among tropical groups. In this study, we examined genome size variation globally and at several taxonomic levels within the Fagaceae. This family has diversified...

Timing for success: expression phenotype and local adaptation related to latitude in the boreal forest tree, Populus balsamifera
submitted by makhlismaarod 2 hours ago - Topic: Forestry
Timing of seasonal dormancy is among the most important traits allowing forest tree populations to span latitudinal gradients of temperature and growing season length. We used RNA-sequencing (RNA-seq) data to identify gene expression differences between latitude-adapted populations and search for elevated genetic differentiation, a signature of adaptation, between northern and southern populati...


Landscape genetics of Persian walnut (Juglans regia L.) across its Asian range
submitted by makhlismaarod 2 hours ago - Topic: Forestry
Persian walnut (Juglans regia L) is an economically important species cultivated worldwide for its wood and nuts. Despite the increasing interest in the development of conservation strategies for walnut germplasm, an accurate and full-scale overview of wild genetic resources of J. regia has not been conducted because natural populations are located in regions of Asia historically difficult to a...

A model for quantitative trait loci mapping, linkage phase, and segregation pattern estimation for a full-sib progeny
submitted by makhlismaarod 2 hours ago - Topic: Forestry
Quantitative trait loci (QTL) mapping is an important approach for the study of the genetic architecture of quantitative traits. For perennial species, inbred lines cannot be obtained due to inbreed depression and a long juvenile period. Instead, linkage mapping can be performed by using a full-sib progeny. This creates a complex scenario because both markers and QTL alleles can have different ...


Mice Lacking NOX2 are Hyperphagic and Store Fat Preferentially in the Liver
submitted by pandhiiponkor 2 hours ago - Topic: Health
Chronic low-grade inflammation is an important contributor to the development of insulin resistance, a hallmark of type 2 diabetes mellitus (T2DM). Obesity and high fat feeding lead to infiltration of immune cells into metabolic tissues, promoting inflammation and insulin resistance. We hypothesized that macrophages from mice lacking NOX2 (Cybb), an essential component of the NADPH oxidase comp...

Automated Quantification of Pancreatic beta-cell Mass
submitted by pandhiiponkor 2 hours ago - Topic: Health
β-cell mass is a parameter commonly measured in studies of islet biology and diabetes. However, the rigorous quantification of pancreatic β-cell mass using conventional histological methods is a time-consuming process. Rapidly evolving virtual slide technology with high-resolution slide scanners and newly developed image analysis tools has a potential to transform β-cell mass mea...

Improved cardiac function and dietary fatty acid metabolism after modest weight loss in subjects with impaired glucose tolerance
submitted by pandhiiponkor 2 hours ago - Topic: Health
Using a novel positron emission tomography (PET) method with oral administration of 14(R,S)-[18F]-fluoro-6-thia-heptadecanoic acid (18FTHA), we recently demonstrated that subjects with impaired glucose tolerance (IGT) display an impairment in cardiac function associated with increased myocardial uptake of dietary fatty acids. Here, we determined whether modest weight loss induced by lifestyle c...

Acylcarnitines activate pro-inflammatory signaling pathways
submitted by pandhiiponkor 2 hours ago - Topic: Health
Incomplete β-oxidation of fatty acids in mitochondria is a feature of insulin resistance and type 2 diabetes mellitus (T2DM). Previous studies revealed that plasma concentrations of medium- and long-chain acylcarnitines (by-products of incomplete β-oxidation) are elevated in type 2 diabetes and insulin resistance. In a previous study, we reported that mixed D, L isomers of C12- or C14...