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Gastric crystal-storing histiocytosis detected with asymptomatic Sjögren’s syndrome: report of a case and summary
submitted by drroe 21 minutes ago - Topic: Health
Crystal-storing histiocytosis (CSH) localized to the stomach is very rare, with only two cases reported to date. The present patient was a 55-year-old woman with no noteworthy symptoms. An area of discoloration was seen in the greater curvature of the gastric body on upper endoscopy by a local ph...



Experimental evidence for trait utility of gill raker number in adaptive radiation of a north temperate fish
submitted by hindrekm 24 minutes ago - Topic: Biology
North temperate fish in post-glacial lakes are textbook examples for rapid parallel adaptive radiation into multiple trophic specialists within individual lakes. Speciation repeatedly proceeded along the benthic–limnetic habitat axis, and benthic–limnetic sister species diverge in the number ...

Selenoneine, a Novel Selenium-Containing Compound, Mediates Detoxification Mechanisms against Methylmercury Accumulation and Toxicity in Zebrafish Embryo
submitted by jisascall 24 minutes ago - Topic: Biology
The selenium (Se)-containing antioxidant selenoneine (2-selenyl-Nα,Nα,Nα-trimethyl-l-histidine) has recently been discovered to be the predominant form of organic Se in tuna blood. Although dietary intake of fish Se has been suggested to reduce methylmercury (MeHg) toxicity, the molecular mech...

Marine-Derived Aspergillus Species as a Source of Bioactive Secondary Metabolites
submitted by jisascall 24 minutes ago - Topic: Biology
This report reviews biologically active secondary metabolites from marine-derived members of the fungal genus Aspergillus. Pharmacological activities and biological roles of the secondary metabolites from marine-derived Aspergillus spp. were addressed in respect of pharmaceutical potential....

PDGF-C: a new performer in the neurovascular interplay
submitted by pgaa 25 minutes ago - Topic: Health
The importance of neurovascular crosstalk in development, normal physiology, and pathologies is increasingly being recognized. Although vascular endothelial growth factor (VEGF), a prototypic regulator of neurovascular interaction, has been studied intensively, defining other important regulators...



Navigating personalized medicine dependent on modular flexibility
submitted by pgaa 25 minutes ago - Topic: Health
Deconstructing networks and rewiring alterable modules in a rational way is critical to optimize drug discovery and develop personalized medicine.

Association of Weather and Anthropogenic Factors for Transmission of Japanese Encephalitis in an Endemic Area of India
submitted by moresiminord 36 minutes ago - Topic: Health
Weather and anthropogenic factors are important determinants for Japanese encephalitis (JE) transmission. During 2008–2010, an increasing trend of JE was observed in Dibrugarh district of Northeast India. The JE cases were found to be clustered between June to October in each year. Monthly mini...

Multi-Institutional Retrospective Cohort Study of Spontaneous Pneumothorax
submitted by dorodero 38 minutes ago - Topic: Health
Spontaneous pneumonia (SP) affects only a subset of patients in a variety of disorders. This multi-institutional study attempted to identify unique clinicopathologic features of spontaneous pneumothorax (SP) in a large cohort. A total of 111 cases from 109 patients were retrieved from 3 instituti...

Unicryptal gallbladder adenomas in a patient with Gardner's syndrome
submitted by dorodero 38 minutes ago - Topic: Health
Gardner's syndrome occurs when mutation of the adenomatous polyposis coli gene is associated with extra-intestinal manifestations in addition to colorectal adenomas. Only eleven cases of gallbladder adenoma in Gardner's syndrome have been previously reported in the literature. We report a case of...

Wound drainages in total hip arthroplasty: to use or not to use? Review of the literature on current practice
submitted by eve 41 minutes ago - Topic: Health
Of this study is to analyze data reported in literature concerning the efficacy of using wound low-vacuum suction drainages in orthopedic surgery after total hip arthroplasty. We analyzed studies concerning the use of drainages in prosthetic hip replacement surgery, performing our research throug...

The Effects of Social Media on Political Participation and Candidate Image Evaluations in the 2012 Iowa Caucuses
submitted by oyb119 43 minutes ago - Topic: Health
Much academic debate has centered on the impact of new technologies on democracy. This study examines the effects of social media on political participation and candidate image evaluations in the first-in-the-nation Iowa caucuses. Multivariate analyses show that social media have no effects on li...

No Place to Belong: Contextualizing Concepts of Mental Health Among Undocumented Immigrant Youth in the United States
submitted by oyb119 43 minutes ago - Topic: Health
This article examines the consequences of undocumented immigration status for those who grow up in the United States. The aim is to examine the relationship between undocumented immigrant status and mental and emotional health. Our efforts focus on undocumented immigrants who arrive as children a...

Decisive role of Reelin signaling during early stages of Alzheimer’s disease
submitted by kleinhev 47 minutes ago - Topic: Health
Alzheimer’s disease (AD) is one of the largest unmet medical concerns of our society. Around 25 million patients worldwide together with their families are still waiting for an effective treatment. We have recently initiated a re-evaluation of our knowledge of the molecular and cellular mechani...

Struggling with daily life and enduring pain”: a qualitative study of the experiences of pregnant women living with pelvic girdle pain
submitted by sasonstontan 47 minutes ago - Topic: Health
Few studies have investigated the experiences of living with pelvic girdle pain (PGP) and its impact on pregnant women’s lives. To address this gap in knowledge, this study investigates the experiences of women living with PGP during pregnancy. A purposive sample, of nine pregnant women with di...

Differential effects of cholinergic and noradrenergic neuromodulation on spontaneous cortical network dynamics
submitted by ojerili 49 minutes ago - Topic: Health
Cholinergic and noradrenergic neuromodulation play a key role in determining overall behavioral state by shaping the underlying cortical network dynamics. The effects of these systems on synaptic and intrinsic cellular targets are quite diverse and a comprehensive understanding of how these neuro...