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Tubular Secretion of Creatinine in Autosomal Dominant Polycystic Kidney Disease: Consequences for Cross-sectional and Longitudinal Performance of Kidney Function Estimating Equations
submitted by ono 10 minutes ago - Topic: Health
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by renal tubular cell proliferation and dedifferentiation, which may influence tubular secretion of creatinine (CCr[TS]). Diagnostic test study. We therefore investigated CCr(TS) in patients with ADPKD and controls and studied ...



Early-Life Overweight Trajectory and CKD in the 1946 British Birth Cohort Study
submitted by ono 10 minutes ago - Topic: Health
Few studies have examined the impact of childhood obesity on later kidney disease, and consequently, our understanding is very limited. Longitudinal population-based cohort. The Medical Research Council National Survey of Health and Development, a socially stratified sample of 5,362 singletons bo...

Fine root dynamics in relation to nutrients in oligotrophic Bornean rain forest soils
submitted by diondro 14 minutes ago - Topic: Biology
The fine roots of plants are key structures enabling soil resource acquisition, yet our understanding of their dynamics and the factors governing them is still underdeveloped, especially in tropical forests. We evaluated whether Bornean tree communities on soils with contrasting resource availabi...

An assessment of validity and responsiveness of generic measures of health-related quality of life in hearing impairment
submitted by nehetj 19 minutes ago - Topic: Biology
This review examines psychometric performance of three widely used generic preference-based measures, that is, EuroQol 5 dimensions (EQ-5D), Health Utility Index 3 (HUI3) and Short-form 6 dimensions (SF-6D) in patients with hearing impairments. A systematic search was undertaken to identify studi...

A conceptual model of health-related quality of life in sarcoidosis
submitted by nehetj 19 minutes ago - Topic: Biology
Sarcoidosis is a multisystem disease that commonly affects the lung, eye, skin, and lymphatic systems. Organ function has been a major focus of treatment outcome with less attention given to more subjective impacts, such as health-related quality of life (HRQL). The purpose of this paper is to pr...



Multidetector computed tomography findings of central bronchopleural fistulas as sequelae of tuberculosis, chemo radiation and trauma: A report of three cases
submitted by joera 21 minutes ago - Topic: Health
A bronchopleural fistula (BPF) is defined as a direct pathway between the bronchial tree or lung parenchyma and the pleural space. Herein, we describe the clinical findings and imaging results of BPFs in three cases. The patients' medical histories revealed that the first had recurrent pulmonary ...

Zooplankton composition along the confinement gradient of the Taranto Sea System (Ionian Sea, South-eastern Italy)
submitted by pondosbiors 30 minutes ago - Topic: Geography
A 2-year study was conducted on 4 interconnected, progressively more confined coastal basins with the aim of describing zooplankton composition and its dynamics. A total of 346 taxa (175 species) were recorded. 24 species were new records for the Italian fauna. Taxa richness was partly attributed...

Peripheral Primitive Neuroectodermal Tumour in a Dog
submitted by dallvit 34 minutes ago - Topic: Agriculture
A 1-year-old German shepherd dog was presented with paraparesis quickly progressing to paraplegia. Magnetic resonance imaging revealed a large mass beneath the thoracolumbar vertebral column infiltrating the spinal canal and resulting in severe extradural compression of the spinal cord. Microscop...

Autophagy: A critical regulator of cellular metabolism and homeostasis
submitted by pandhiiponkor 36 minutes ago - Topic: Biology
Autophagy is a dynamic process by which cytosolic material, including organelles, proteins, and pathogens, are sequestered into membrane vesicles called autophagosomes, and then delivered to the lysosome for degradation. By recycling cellular components, this process provides a mechanism for adap...

Biotransfer, Bioaccumulation and Effects of Herbivore Dietary Co, Cu, Ni, and Zn on Growth and Development of the Insect Predator Podisus maculiventris (Say)
submitted by motgerl 42 minutes ago - Topic: Biology
Increased metal availability in the environment can be detrimental for the growth and development of all organisms in a food web. In part, this toxicity is due to biotransfer or bioaccumulation of metals between trophic levels. We evaluated the survival, growth, and development of a generalist He...

Predicting dedifferentiation in liposarcoma: a proteomic approach
submitted by glinn234 59 minutes ago - Topic: Health
There are no known morphologic characteristics, cytogenetic aberrations, or molecular alterations predictive of dedifferentiation in liposarcomas. Identification of such a prognostic marker could potentially affect surgical and adjuvant therapy and/or follow-up surveillance for these patients. Tw...

How healthcare provider talk with parents of children following severe traumatic brain injury is perceived in early acute care
submitted by friidamzn 1 hour ago - Topic: Health
Healthcare provider talk with parents in early acute care following children's severe traumatic brain injury (TBI) affects parents' orientations to these locales, but this connection has been minimally studied. This lack of attention to this topic in previous research may reflect providers' and r...

Post-exercise left ventricular dysfunction measured after a long-duration cycling event
submitted by ftamin 1 hour ago - Topic: Health
In this research, an extension to our previous work published in the Clinical Journal of Sports Medicine in 2009, we studied subjects that differed in terms of age and training status and assessed the impact of prolonged exercise on systolic and left ventricular diastolic function and cardiac bio...

A qualitative study of health information technology in the Canadian public health system
submitted by ondribi889 1 hour ago - Topic: Health
Although the adoption of health information technology (HIT) has advanced in Canada over the past decade, considerable challenges remain in supporting the development, broad adoption, and effective use of HIT in the public health system. Policy makers and practitioners have long recognized that i...

Modelling the geographical distribution of soil-transmitted helminth infections in Bolivia
submitted by lene253541 1 hour ago - Topic: Health
The prevalence of infection with the three common soil-transmitted helminths (i.e. Ascaris lumbricoides, Trichuris trichiura and hookworm) in Bolivia is among the highest in Latin America. However, the spatial distribution and burden of soil-transmitted helminthiasis are poorly documented. We ana...