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Study Habits, Motives, and Strategies of College Students With Symptoms of ADHD
submitted by larroeni6 18 minutes ago - Topic: Health
Studies on ADHD in educational settings indicate that a student’s motivation for learning is significantly related with the student’s grade point average. The present study examined the relationship between ADHD symptoms and student academic achievement by considering the student’s approach to and motivation for learning. Participants completed a questionnaire that breaks down...



Mild Traumatic Brain Injury and ADHD: A Systematic Review of the Literature and Meta-Analysis
submitted by larroeni6 18 minutes ago - Topic: Health
This study investigated the association between mild traumatic brain injury (mTBI) and ADHD, which increases risk of injuries and accidents. We conducted a systematic review and meta-analysis of studies that examined the relationship between mTBI and ADHD. Five studies, comprising 3,023 mTBI patients and 9,716 controls, fit our a priori inclusion and exclusion criteria. A meta-analysis found a ...

Serum cystatine C and serum and urine NGAL in the kidney function assessment of patients with MGUS
submitted by drmoraf 28 minutes ago - Topic: Health
Monoclonal gammopathy of undetermined significance (MGUS) occurs without other symptoms; although, monoclonal proteins can cause kidney injuries. Here, we assessed kidney function and identified the best follow-up parameters in patients with MGUS without kidney damage symptoms. MethodologyForty-six patients with MGUS were included in the study group. The control group (CRT, n=23) consisted of h...

Effects of age and zinc supplementation on transport properties in the jejunum of piglets
submitted by kora 31 minutes ago - Topic: Biology
Zinc is effective in the prevention and treatment of post-weaning diarrhoea and in promoting piglet growth. Its effects on the absorption of nutrients and the secretory capacity of the intestinal epithelium are controversial. We investigated the effects of age, dietary pharmacological zinc supplementation and acute zinc exposure in vitro on small-intestinal transport properties of weaned piglet...

Immunohistochemical study on localization of serotonin immunoreactive cells in the gastrointestinal tract of the European catfish (Silurus glanis, L.)
submitted by kora 31 minutes ago - Topic: Biology
In this study, it was aimed to identify the distribution of serotonin immunoreactive cells within the gastrointestinal tract (GIT) of European catfish (Silurus glanis). For this purpose, the tissue samples were taken from the stomach (cardia, fundus and pylorus region) and intestine (anterior, middle and posterior region). They were examined by applying the avidin-biotin-immunoperoxidase method...



Role of nitric oxide synthase isoforms for ophthalmic artery reactivity in mice
submitted by mffrietos 44 minutes ago - Topic: Health
Nitric oxide synthases (NOS) are involved in regulation of ocular vascular tone and blood flow. While endothelial NOS (eNOS) has recently been shown to mediate endothelium-dependent vasodilation in mouse retinal arterioles, the contribution of individual NOS isoforms to vascular responses is unknown in the retrobulbar vasculature. Moreover, it is unknown whether the lack of a single NOS isoform...

Extracellular matrix remodeling during retinal development
submitted by mffrietos 45 minutes ago - Topic: Health
The extracellular matrix (ECM) consists of a versatile and dynamic meshwork of proteoglycans and glycoproteins and plays an important functional role in complex tissues such as the developing retina. ECM forms the milieu surrounding retinal cells, constitutes basement membranes and provides structural as well as mechanical support. In addition, ECM molecules regulate the retinal homeostasis and...


Serial explant culture provides novel insights into the potential location and phenotype of corneal endothelial progenitor cells
submitted by mffrietos 45 minutes ago - Topic: Health
The routine cultivation of human corneal endothelial cells, with the view to treating patients with endothelial dysfunction, remains a challenging task. While progress in this field has been buoyed by the proposed existence of progenitor cells for the corneal endothelium at the corneal limbus, strategies for exploiting this concept remain unclear. In the course of evaluating methods for growing...

Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells
submitted by mffrietos 45 minutes ago - Topic: Health
Chronic inflammation is a key pathogenic process in age-related macular degeneration (AMD). Amyloid-beta (Aβ) is a constituent of AMD drusen and promotes the activation of NLRP3 inflammasome which facilitates the production of cytokines. We investigated the role of transcription factor NF-κB in the activation of inflammasome in the RPE and the effect of vinpocetine, a dietary supplement with ...


Tg(Grm1) transgenic mice: A murine model that mimics spontaneous uveal melanoma in humans?
submitted by mffrietos 45 minutes ago - Topic: Health
Although rare, uveal melanoma (UM) is the most common primary intraocular tumor in adults. About half of UM patients develop metastatic disease typically in the liver and die within a short period, due to ineffective systemic therapies. UM has unique and distinct genetic features predictive of metastasis. Animal models are required to improve our understanding of therapeutic options in dissemin...

Role of an extracellular chaperone, clusterin in the pathogenesis of pseudoexfoliation syndrome and pseudoexfoliation glaucoma
submitted by mffrietos 45 minutes ago - Topic: Health
Pseudoexfoliation (PEX), an age related disorder is a prominent contributor to secondary glaucoma. Earlier studies have suggested the involvement of clusterin in the development of PEX. We designed a case-control study to understand the role of clusterin single nucleotide polymorphisms (SNPs) in PEX and analyzed the role of risk alleles in the disease. Genotyping of SNPs in 136 PEX patients and...


Facing the challenge of teaching emotions to individuals with low- and high-functioning autism using a new Serious game: a pilot study
submitted by presteni 52 minutes ago - Topic: Health
It is widely accepted that emotion processing difficulties are involved in Autism Spectrum Conditions (ASC). An increasing number of studies have focused on the development of training programs and have shown promising results. However, most of these programs are appropriate for individuals with high-functioning ASC (HFA) but exclude individuals with low-functioning ASC (LFA). We have developed...

Safety and Efficacy of Indigenous Equine Antithymocyte Globulin Along with Cyclosporine in Subjects with Acquired Aplastic Anemia
submitted by ondriwrjb 1 hour ago - Topic: Health
To confirm the safety and efficacy of an indigenous equine antithymocyte globulin (eATG) along with cyclosporine in Indian subjects with acquired aplastic anaemia. Subjects >2 years old with acquired aplastic anaemia were enrolled at six hospitals between April 2011 and February 2013, after approval from respective Ethics Committees. Equine ATG at a dose of 40 mg/kg/day was infused for 4 da...

Diagnostic and Therapeutic Quandaries in a Patient with Primary Hepatic Lymphoma and Concurrent Hepatitis C Infection
submitted by ondriwrjb 1 hour ago - Topic: Health
Primary hepatic lymphoma (PHL) is a very rare sub-type of non-Hodgkin’s lymphoma and hepatitis C infection may be a contributory factor. The association of hepatitis C infection and PHL causes difficulties in management since safety of rituximab in such situations is unclear due to lack of evidence. The role of anti-viral therapy in combination with chemotherapy is also uncertain. We describe...

Juvenile Myelomonocytic Leukemia in India: Cure Remains a Distant Dream!
submitted by ondriwrjb 1 hour ago - Topic: Health
There is paucity of outcome data regarding juvenile myelomonocytic leukemia from India. We report a series of eight children. Three had monosomy 7 and one had complex cytogenetics. One with Down’s syndrome recovered spontaneously. Three refused therapy of whom only one is alive with disease. One died post chemotherapy. Three underwent allogeneic stem cell transplant after protracted delay wit...