Biology Agriculture Aquaculture Horticulture Postharvest Forestry Geography Environment Health





View All

Systemic Administration of the Neurotensin NTS1-Receptor Agonist PD149163 Improves Performance on a Memory Task in Naturally Deficient Male Brown Norway Rats
submitted by silsay74 18 minutes ago - Topic: Health
Agonists for the neurotensin NTS1 receptor consistently exhibit antipsychotic effects in animal models without producing catalepsy, suggesting that NTS1-receptor agonists may be a novel class of drugs to treat schizophrenia. Moreover, studies utilizing NTS1 agonists have reported improvements in some aspects of cognitive functioning, including prepulse inhibition and learning procedures, which ...



A Critical Review of the Literature on Attentional Bias in Cocaine Use Disorder and Suggestions for Future Research
submitted by silsay74 18 minutes ago - Topic: Health
Cocaine use disorder (CUD) continues to be an important public health problem, and novel approaches are needed to improve the effectiveness of treatments for CUD. Recently, there has been increased interest in the role of automatic cognition such as attentional bias (AB) in addictive behaviors, and AB has been proposed to be a cognitive marker for addictions. Automatic cognition may be particul...

Air-kerma evaluation at the maze entrance of HDR brachytherapy facilities
submitted by mokali 18 minutes ago - Topic: Health
In the absence of procedures for evaluating the design of brachytherapy (BT) facilities for radiation protection purposes, the methodology used for external beam radiotherapy facilities is often adapted. The purpose of this study is to adapt the NCRP 151 methodology for estimating the air-kerma rate at the door in BT facilities. Such methodology was checked against Monte Carlo (MC) techniques u...

Respiratory Hemodynamics in the Hepatic Veins—Normal Pattern
submitted by phainex 20 minutes ago - Topic: Health
Doppler interrogation of blood flow in the hepatic veins (HVs) is a part of any comprehensive echocardiographic examination. Data derived from the HV Doppler provide a useful tool for the assessment of right heart function. Beyond its dependence on the cardiac cycle, right heart hemodynamics, and compliance of the liver parenchyma, blood flow in the HVs is influenced by the respiratory cycle. S...

Three-Dimensional Echocardiography Guided Closure of Complex Multiple Atrial Septal Defects
submitted by phainex 20 minutes ago - Topic: Health
Transcatheter closure of complex multiple atrial septal defects (ASDs) remains a challenge. We describe our clinical experience with staged device deployment in a patient with multiple ASDs using four Amplatzer septal occluder devices. Three-dimensional transesophageal echocardiography imaging contributed not only to the therapeutic guidance of successful device deployment but also to the decis...



Tendon Progenitor Cells in Injured Tendons Have Strong Chondrogenic Potential: The CD105-Negative Subpopulation Induces Chondrogenic Degeneration
submitted by sason227 21 minutes ago - Topic: Biology
To study the cellular mechanism of the tendon repair process, we used a mouse Achilles tendon injury model to focus on the cells recruited to the injured site. The cells isolated from injured tendon 1 week after the surgery and uninjured tendons contained the connective tissue progenitor populations as determined by colony-forming capacity, cell surface markers and multipotency. When the injure...

Governance struggles and policy processes in disaster risk reduction: A case study from Nepal
submitted by tormik97 27 minutes ago - Topic: Geography
In the neo-liberal climate of reduced responsibility for the state, alongside global platforms established to implement the Hyogo Framework for Action, a new arena opens for a multitude of stakeholders to engage in disaster risk reduction (DRR). The key role that the state can play in instituting effective DRR tends to receive little attention, yet in situations where the state apparatus is wea...


Assessing fit in Bayesian models for spatial processes
submitted by f2060o 28 minutes ago - Topic: Environment
Gaussian random fields are frequently used to model spatial and spatial–temporal data, particularly in geostatistical settings. As much of the attention of the statistics community has been focused on defining and estimating the mean and covariance functions of these processes, little effort has been devoted to developing goodness-of-fit tests to allow users to assess the models' adequacy. We...

Statistical modeling and forecasting of fruit crop phenology under climate change
submitted by f2060o 28 minutes ago - Topic: Environment
Phenology, the study of the association between biological development stages and variations in climate, has greatly increased in importance because of concerns arising from climate change. This paper presents a general stochastic approach to the modeling of the relationship between phenological events and climate variables, and gives a prediction method based on this approach to provide full p...


Efficacy of Sporicidal Wipes for Inactivation of a Bacillus anthracis Surrogate
submitted by loeloempix 28 minutes ago - Topic: Biology
To evaluate five commercially available sporicidal wipes and two disinfecting wipes for their ability to inactivate Bacillus atrophaeus spores deposited onto various material surfaces. and ResultsDecontamination efficacy of the wipes was initially tested on glass Petri dishes (150 mm diameter). Following exposure for a specified time of contact, survival of the spores was assessed by quantifica...

Trigger factor assisted folding of the recombinant epoxide hydrolases identified from C. pelagibacter and S. nassauensis
submitted by oenat 28 minutes ago - Topic: Biology
Epoxide hydrolases (EHs), are enantioselective enzymes as they catalyze the kinetic resolution of racemic epoxides into the corresponding enantiopure vicinal diols, which are useful precursors in the synthesis of chiral pharmaceutical compounds. Here, we have identified and cloned two putative epoxide hydrolase genes (cpeh and sneh) from marine bacteria, C. pelagibacter ubique and terrestrial b...


Expression and purification of active, stabilized trimethyllysine hydroxylase
submitted by oenat 28 minutes ago - Topic: Biology
Trimethyllysine hydroxylase (TMLH) catalyses the first step in carnitine biosynthesis – the conversion of N6,N6,N6-trimethyl-L-lysine to 3-hydroxy-N6,N6,N6-trimethyl-L-lysine. By changing carnitine availability it is possible to optimize cardiac energy metabolism, that is beneficial under certain ischemic conditions. Previous efforts have been devoted towards the inhibition of gamma-butyrobet...

Body Size and Risk of Spontaneous Abortion among Danish Pregnancy Planners
submitted by grenzy 29 minutes ago - Topic: Health
Several studies indicate that female obesity increases the risk of spontaneous abortion (SAB). Central adiposity, height, and location of typical weight gain have not been examined as risk factors for SAB. We examined the associations between selected anthropometric factors and risk of SAB among 5132 women enrolled in a Danish Internet-based prospective cohort study of pregnancy planners. We us...

Impact of Instruction in the Creighton Model FertilityCare System on Time to Pregnancy in Couples of Proven Fecundity: Results of a Randomised Trial
submitted by grenzy 29 minutes ago - Topic: Health
The Creighton Model FertilityCare System (CrMS) teaches women to identify days when intercourse is likely to result in pregnancy. We sought to assess the impact of the CrMS on time to pregnancy (P), via per-cycle pregnancy rates (fecundability). We conducted a parallel randomised trial at the University of Utah School of Medicine, 2003–06. Women ages 18–35 years, in a relationship of proven...

Anaemia of Pregnancy, Perinatal Outcomes and Children's Developmental Vulnerability: a Whole-of-Population Study
submitted by grenzy 29 minutes ago - Topic: Health
There is limited longitudinal data from high-income countries on the sequelae of anaemia during pregnancy. The aim of this study is to examine whether anaemia of pregnancy is associated with adverse perinatal outcomes and with children's developmental vulnerability. We conducted a population-based study to link routinely collected government administrative data that involved all live births in ...