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Early and late postoperative seizure outcome in 97 patients with supratentorial meningioma and preoperative seizures: a retrospective study
submitted by ox451apcndr 18 minutes ago - Topic: Health
We identified factors associated with early and late postoperative seizure control in patients with supratentorial meningioma plus preoperative seizures. In this retrospective study, univariate analysis and multivariate logistic regression analysis compared 24 clinical variables according to the ...



Caloric restriction reduces edema and prolongs survival in a mouse glioma model
submitted by ox451apcndr 18 minutes ago - Topic: Health
Regardless of their cell type of origin, all aggressive brain tumors, such as malignant gliomas and metastatic tumors produce brain edema, which is an important cause of patient morbidity and mortality. Caloric restriction (CR) has long been recognized as a natural therapy that improves health, p...

The cytotoxic effect of β-elemene against malignant glioma is enhanced by base-excision repair inhibitor methoxyamine
submitted by ox451apcndr 18 minutes ago - Topic: Health
This study investigated the effects of β-elemene + methoxyamine, a DNA base-excision repair inhibitor, on the inhibition of glioma growth. We treated C6 and SHG44 glioma cells with β-elemene and methoxyamine individually or in combinations, and subsequently analyzed cellular survivals by M as...

Comparative analysis of survival, treatment, cost and resource use among patients newly diagnosed with brain metastasis by initial primary cancer
submitted by ox451apcndr 18 minutes ago - Topic: Health
Brain metastases are a frequent complication of many systemic cancers and portend a poor prognosis. This retrospective analysis of health claims data compared survival, treatment and health care utilization and costs in patients with brain metastasis by primary tumor site. Adult commercial and Me...

MicroRNA biomarkers in glioblastoma
submitted by ox451apcndr 18 minutes ago - Topic: Health
Recent research suggests that deregulation of microRNAs (miRNAs) is involved in initiation and progression of many cancers, including gliomas and that miRNAs hold great potential as future diagnostic and therapeutic tools in cancer. MiRNAs are a class of short non-coding RNA sequences (18–24 nu...



LPS-Stimulating Astrocyte-Conditioned Medium Causes Neuronal Apoptosis Via Increasing CDK11p58 Expression in PC12 Cells Through Downregulating AKT Pathway
submitted by orviswopnel 22 minutes ago - Topic: Health
Activation of astrocytes in central nervous system inflammation leads to a disturbance of crosstalk between astrocytes and neurons, and that this may contribute to the death of neurons. CDK11p58 is a member of the large family of p34cdc2-related kinases. It specifically expresses in G2/M phase of...

A re-evaluation of a case–control model with contaminated controls for resource selection studies
submitted by hagh 25 minutes ago - Topic: Biology
A common sampling design in resource selection studies involves measuring resource attributes at sample units used by an animal and at sample units considered available for use. Few models can estimate the absolute probability of using a sample unit from such data, but such approaches are general...

Multi-trophic resource selection function enlightens the behavioural game between wolves and their prey
submitted by hagh 25 minutes ago - Topic: Biology
Habitat selection strategies translate into movement tactics, which reckon with the predator–prey spatial game. Strategic habitat selection analysis can therefore illuminate behavioural games. Cover types at potential encounter sites (i.e. intersections between movement paths of predator and pr...

In vitro motor patterns and electrophysiological changes in patients with colonic diverticular disease
submitted by kinwelkens 26 minutes ago - Topic: Health
The underlying mechanism responsible for motility changes in colonic diverticular disease (DD) is still unknown. In the present study, our aim was to investigate the structural and in vitro motor changes in the sigmoid colon of patients with DD.Muscle bath, microelectrodes and immunohistochemical...

The nutritional impact of diverting stoma-related complications in elderly rectal cancer patients
submitted by kinwelkens 26 minutes ago - Topic: Health
Diverting stomas following rectal cancer surgery can affect patients' quality of life, and their complications may negatively affect patients' long-term outcomes and quality of life. The purpose of this study is to investigate the relationship between diverting stoma-related complications and nut...

Expression and localization of axin 2 in colorectal carcinoma and its clinical implication
submitted by kinwelkens 26 minutes ago - Topic: Health
Aberrant activation of the Wnt/β-catenin pathway plays a major role in the development of colorectal carcinoma (CRC). Axin 2 is a key protein of this pathway and is upregulated in CRC. Here, we investigated RNA- and protein expression of axin 2 in CRC tissues at the single cell level. Moreover, ...

A survey of power density of light-curing units used in private dental offices in Changchun City, China
submitted by mgroceo 27 minutes ago - Topic: Health
This study investigated power density and relevant information related to light-curing units used in private dental offices in Changchun City, China. The power density of 196 light-curing units used in private dental offices in Changchun City was measured using a simple random sampling method. Re...

RUNX3 confers sensitivity to pheophorbide a-photodynamic therapy in human oral squamous cell carcinoma cell lines
submitted by mgroceo 27 minutes ago - Topic: Health
Photodynamic therapy (PDT) with photosensitizer is one of the promising modalities for cancer treatment. For clinical use of PDT, screening process should be preceded to enhance sensitivity to PDT. Thus, we investigated a molecular biomarker to determine the sensitivity to pheophorbide a (Pa)-PDT...

Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient: Case report and literature review
submitted by daagdowis 29 minutes ago - Topic: Health
Colchicine is a relatively safe medication that is widely used for both prevention and treatment of gout attack. However, serious adverse events, including myoneuropathy and multiorgan failure, have been reported. We report a case of colchicine-induced myoneuropathy in a female kidney transplant ...

A case of successful antibiotic treatment from Pseudomonas stutzeri-induced peritonitis without catheter removal in continuous ambulatory peritoneal dialysis
submitted by daagdowis 29 minutes ago - Topic: Health
Pseudomonas stutzeri is a Gram-negative, rod-shaped, motile, single polar-flagellated, soil bacterium that was first isolated from human spinal fluid and is widely distributed in the environment. It was isolated as an uncommon opportunistic pathogen from humans, and a few cases of P. stutzeri-ind...