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Rhein lysinate inhibits monocyte adhesion to human umbilical vein endothelial cells by blocking p38 signaling pathway
submitted by mpeipir 34 minutes ago - Topic: Health
The objective of this study was to investigate the effect of rhein lysinate (RHL) on monocyte adhesion and its mechanism. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (M) assay was used to determine the growth inhibition by drugs. The monocyte chemoattractant protein (MCP)-1 level...



The cognitive-interpersonal maintenance model of anorexia nervosa revisited: a summary of the evidence for cognitive, socio-emotional and interpersonal predisposing and perpetuating factors
submitted by kwblost 46 minutes ago - Topic: Health
To describe the evidence base relating to the Cognitive-Interpersonal Maintenance Model for anorexia nervosa (AN). A Cognitive-Interpersonal Maintenance Model maintenance model for anorexia nervosa was described in 2006. This model proposed that cognitive, socio-emotional and interpersonal elemen...

Effects of wave exposure, temperature and epibiont fouling on byssal thread production and growth in the blue mussel, Mytilus edulis, in the Gulf of Maine
submitted by mclezodo 50 minutes ago - Topic: Biology
Blue mussels (Mytilus edulis) need a strong byssal attachment to remain anchored on wave swept shores. Byssogenesis and mussel growth can be affected by abiotic factors, as well as by biotic interactions. Using short- and long-term field deployments of artificially-fouled mussels in coastal New H...

Sympathetic Afferent Stimulation Inhibits Central Vagal Activation Induced by Intravenous Medetomidine in Rats
submitted by spoz 50 minutes ago - Topic: Biology
To examine whether sympathetic afferent stimulation (SAS) inhibits central vagal activation induced by α2-adrenergic stimulationMethodsIn anaesthetized Wistar Kyoto rats, a cardiac microdialysis technique was applied to the left ventricle, and the effect of α2-adrenergic stimulation by medetomi...

Progesterone metabolite influence feeding behaviour
submitted by spoz 50 minutes ago - Topic: Biology
Obesity is increasing worldwide and is associated with increased risk of developing metabolic diseases. One of the factors that have been demonstrated to influence the regulation of appetite and food intake is the different sex hormones, one of these being progesterone that in humans increase foo...



Analysis of S. Epidermidis icaA and icaD genes by polymerase chain reaction and slime production: a case control study
submitted by ohjarth 55 minutes ago - Topic: Health
Staphylococcus epidermidis is a common pathogen in medical device-associated infections and have an ability to form adherent slime. We aimed to study the effects of icaA and icaD genes on the slime formation of Staphylococcus epidermidis associated with catheter-associated infections. S. epidermi...

Representation and learning in motor action – Bridges between experimental research and cognitive robotics
submitted by mojedh7 59 minutes ago - Topic: Health
To gain a better understanding of the functionality of representation and categorization in action and interaction, it is fundamental that researchers understand how movements are represented in long-term memory. It is our position that human motor control requires that our actions be planned and...

A Case of Philadelphia Chromosome Positive Myeloproliferative Neoplasm in a Pregnant Woman with Unusual Primary Myelofibrosis Features
submitted by vectar 1 hour ago - Topic: Health
Myeloproliferative neoplasms (MPNs) are traditionally separated into BCR-ABL-positive chronic myeloid leukemia (CML), and BCR-ABL-negative MPNs including primary myelofibrosis (PMF), essential thrombocythemia (ET), and so forth. One of the diagnostic requirements for PMF and ET is the absence of ...

Age-related changes in fine motion direction discriminations
submitted by wonmohzaz 1 hour ago - Topic: Health
The present study used an equivalent noise method to characterize the sources of reduced performance in fine discrimination of motion with age. We varied the density of the displays, the speed and speed variability and the temporal correlation of dots’ motion in successive frames to assess thei...

The role of the cross-sensory error signal in visuomotor adaptation
submitted by wonmohzaz 1 hour ago - Topic: Health
Reaching to targets with misaligned visual feedback of the hand leads to changes in proprioceptive estimates of hand position and reach aftereffects. In such tasks, subjects are able to make use of two error signals: the discrepancy between the desired and actual movement, known as the sensorimot...

Place it on the side! Evaluation of stickers’ positions on test cars used in field studies
submitted by glniwtan 1 hour ago - Topic: Health
An important question in field studies concerning mobility is where on the vehicles to apply labels of the involved institutions. Research institutions and participating companies might typically have conflicting ideas concerning the design and labels as some want to avoid manipulation of the par...

Palatine tonsillar metastasis of rectal adenocarcinoma: a case report and literature review
submitted by denaform 1 hour ago - Topic: Health
Cases of primary colorectal adenocarcinoma metastasized to the palatine tonsil are extremely rare. To the best of our knowledge, only 10 cases have thus far been previously documented in the English literature. A 37-year-old Chinese woman presented with a right palatine tonsil swelling and odynop...

Copy number variation-based polymorphism in a new pseudoautosomal region 3 (PAR3) of a human X-chromosome-transposed region (XTR) in the Y chromosome
submitted by foizihkofe 1 hour ago - Topic: Biology
A 3.5-Mb region of the X chromosome underwent duplication and transposition to the Y chromosome ~5–6 Mya. This X-transposed-region (XTR) originated at Xq21.3 and was inserted at Yp11.2. The two locations have 98.78 % homology and a high concentration of tandem repeats. In whole-genome scans o...

CGRP inhibits norepinephrine induced apoptosis with restoration of Bcl-2/Bax in cultured cardiomyocytes of rat
submitted by gono3119 1 hour ago - Topic: Health
Calcitonin gene related peptide (CGRP) and norepinephrine (NE) may interact in acute myocardial ischemia, protecting cardiomyocytes but the underlying mechanism is unclear. Here we investigated the correlation of the anti-apoptotic effect of CGRP with the change of Bcl-2/Bax. Cultured cardiomyocy...

Enhancement of IGF-2–induced neurite outgrowth by IGF-binding protein-2 and osteoglycin in SH-SY5Y human neuroblastoma cells
submitted by gono3119 1 hour ago - Topic: Health
A previous study using a mouse model of depression showed that chronic immobilization stress (CIS) reduces levels of insulin-like growth factor (IGF)-2, IGF binding protein 2 (IGFBP2), osteoglycin, and fibromodulin in the amygdala. Here, using human neuroblastoma cells, we tested whether these fo...