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Redundant function of two Arabidopsis COPII components, AtSec24B and AtSec24C, is essential for male and female gametogenesis
submitted by oprenciss61 14 minutes ago - Topic: Agriculture
AbstractAnterograde vesicle transport from the endoplasmic reticulum to the Golgi apparatus is the start of protein transport through the secretory pathway, in which the transport is mediated by coat protein complex II (COPII)-coated vesicles. Therefore, most proteins synthesized on the endoplasm...



Increased root oxygen uptake in pea plants responding to non-self neighbors
submitted by oprenciss61 14 minutes ago - Topic: Agriculture
Recent studies have demonstrated that plants alter root growth and decrease competition with roots of the same individual (self); however, the physiological traits accompanying this response are still widely unknown. In this study, we investigated the effect of root identity on gas exchange in th...

Inter-subject alignment of human cortical anatomy using functional connectivity
submitted by rodasistros 15 minutes ago - Topic: Health
Inter-subject alignment of functional MRI (fMRI) data is necessary for group analyses. The standard approach to this problem matches anatomical features of the brain, such as major anatomical landmarks or cortical curvature. Precise alignment of functional cortical topographies, however, cannot b...

Connectivity-based neurofeedback: Dynamic causal modeling for real-time fMRI
submitted by rodasistros 15 minutes ago - Topic: Health
Neurofeedback based on real-time fMRI is an emerging technique that can be used to train voluntary control of brain activity. Such brain training has been shown to lead to behavioral effects that are specific to the functional role of the targeted brain area. However, real-time fMRI-based neurofe...

Distinct encoding of risk and value in economic choice between multiple risky options
submitted by rodasistros 15 minutes ago - Topic: Health
Neural encoding of value-based stimuli is suggested to involve representations of summary statistics, including risk and expected value (EV). A more complex, but ecologically more common, context is when multiple risky options are evaluated together. However, it is unknown whether encoding relate...



A Transgenic Zebrafish Model of a Human Cardiac Sodium Channel Mutation Exhibits Bradycardia, Conduction-System Abnormalities and Early Death
submitted by vejoykamor 18 minutes ago - Topic: Health
The recent exponential increase in human genetic studies due to the advances of next generation sequencing has generated unprecedented numbers of new gene variants. Determining which of these are causative of human disease is a major challenge. In-vitro studies and murine models have been used to...

Lagooning of wastewaters favors dissemination of clinically relevant Pseudomonas aeruginosa
submitted by drmoraf 19 minutes ago - Topic: Biology
The significance of wastewater treatment lagoons (WWTLs) as point sources of clinically relevant Pseudomonas aeruginosa that can disseminate through rural and peri-urban catchments was investigated. A panel of P. aeruginosa strains collected over three years from WWTLs and community-acquired infe...

Effects of Ellagic Acid on Angiogenic Factors in Prostate Cancer Cells
submitted by blockhiot 20 minutes ago - Topic: Health
Several natural antioxidants, including ellagic acid (EA), have been reported to have chemotherapeutic activity in vivo and in vitro settings. Cytochrome P450 (CYP) activity and synthesis of both epoxyeicosatrienoic acids (EETs) and 20-hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE), together w...

Mechanotherapy: revisiting physical therapy and recruiting mechanobiology for a new era in medicine
submitted by pgaa 22 minutes ago - Topic: Health
It has long been thought that the effectiveness and efficiency of physical therapy would improve if our understanding of the cell biology/biochemistry that participates in mechanics could be improved. Traditional physical therapy focuses primarily on rehabilitation, but recent developments in mec...

Infant feeding in the context of HIV: a qualitative study of health care workers’ knowledge of recommended infant feeding options in Papua New Guinea
submitted by forilolefeyoh 26 minutes ago - Topic: Health
Interventions to prevent mother to child transmission of human immunodeficiency virus (HIV) during childbirth and breastfeeding can reduce HIV infections in infants to less than 5% in low and middle income countries. The World Health Organization (WHO) recommends all mothers, regardless of their ...

Planning of Electroporation-Based Treatments Using Web-Based Treatment-Planning Software
submitted by majtobo3521 27 minutes ago - Topic: Biology
Electroporation-based treatment combining high-voltage electric pulses and poorly permanent cytotoxic drugs, i.e., electrochemotherapy (ECT), is currently used for treating superficial tumor nodules by following standard operating procedures. Besides ECT, another electroporation-based treatment, ...

Effect of Lycopene Application in Rats with Experimental Diabetes Using Lipoprotein, Paraoxonase and Cytokines
submitted by majtobo3521 27 minutes ago - Topic: Biology
This study was conducted with the purpose of researching the effect of lycopene application on lipoprotein, paraoxonase (PON) and cytokines that are projected to be used in the diagnosis and treatment of diabetes by making experimental diabetes. At the end of a 1-month trial period, under ether a...

On the Electroporation Thresholds of Lipid Bilayers: Molecular Dynamics Simulation Investigations
submitted by majtobo3521 27 minutes ago - Topic: Biology
Electroporation relates to the cascade of events that follows the application of high electric fields and that leads to cell membrane permeabilization. Despite a wide range of applications, little is known about the electroporation threshold, which varies with membrane lipid composition. Here, us...

Bird communities in habitats along a successional gradient: Divergent patterns of species richness, specialization and threat
submitted by eaono2095 27 minutes ago - Topic: Biology
The long history of human influence on northern temperate landscapes has created a mosaic of successional stages, from closed forest to open grassland. Various species thus adapted to different habitats and it is interesting to explore how these differences in species composition among particular...

Using Malmquist Indices to evaluate environmental impacts of alternative land development scenarios
submitted by brodwelkens 28 minutes ago - Topic: Biology
The degree to which regions can produce desirable socioeconomic and environmental outcomes while consuming fewer resources and producing fewer undesirable outcomes can be viewed as measure of productivity. Economists have frequently used Malmquist Indices to evaluate intertemporal productivity ch...