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The Role of beta-Adrenergic Blockers in Parkinson's Disease: Possible Genetic and Cell-Signaling Mechanisms
submitted by jasicongos 20 minutes ago - Topic: Health
Genetic studies have identified numerous factors linking β-adrenergic blockade to Parkinson’s disease (PD), including human leukocyte antigen genes, the renin–angiotensin system, poly(adenosine diphosphate-ribose) polymerase 1, nerve growth factor, vascular endothelial growth fac...



Comparison of 2 Diagnostic Criteria for the Behavioral Variant of Frontotemporal Dementia
submitted by jasicongos 20 minutes ago - Topic: Health
The aim of this study was to compare the applicability of the 1998 consensus diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD) with the recently proposed diagnostic criteria of the International bvFTD Criteria Consortium (FTDC).>We reviewed each individual item in ...

Individual and Contextual-Level Factors Associated with Continuity of Care for Adults with Schizophrenia
submitted by savarobor 21 minutes ago - Topic: Health
This retrospective cohort study examined rates of conformance to continuity of care treatment guidelines and factors associated with conformance for persons with schizophrenia. Subjects were 8,621 adult Ohio Medicaid recipients, aged 18–64, treated for schizophrenia in 2004. Information on indi...

Continuous intracorneal ring implantation for keratoconus using a femtosecond laser
submitted by osebliy 24 minutes ago - Topic: Health
To assess the clinical outcomes after continuous intracorneal ring (ICR) implantation for the management of keratoconus using femtosecond laser technology. Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran. Prospective nonrandomized consecutive case series. All patients pre...

Managing aggression and violence: The clinician's role in contemporary mental health care
submitted by mpeipir 24 minutes ago - Topic: Health
From time to time misconceptions about violence risk assessment raise debate about the role mental health professionals play in managing aggression, with associated concerns about the utility of violence risk assessment. This paper will address some of the misconceptions about risk assessment in ...



Cortical thickness changes in the non-lesioned hemisphere associated with non-paretic arm immobilization in modified CI therapy
submitted by chaanshiin 27 minutes ago - Topic: Health
Recent evidence suggests that immobilization of the upper limb for 2–3weeks induces changes in cortical thickness as well as motor performance. In constraint induced (CI) therapy, one of the most effective interventions for hemiplegia, the non-paretic arm is constrained to enforce the use of th...

Composition of green turtle feeding aggregations along the Japanese archipelago: implications for changes in composition with current flow
submitted by oot 28 minutes ago - Topic: Biology
In order to develop effective conservation strategies for endangered migratory species, the link between feeding and breeding grounds needs to be clarified. In this study, the genetic compositions of consecutive Japanese feeding aggregations of green turtles (Chelonia mydas) along the Kuroshio Cu...

Preparation, optimization, and in-vitro/in-vivo/ex-vivo characterization of chitosan-heparin nanoparticles: drug-induced gelation
submitted by dacrhio13 33 minutes ago - Topic: Health
Management of blood coagulation-related diseases is currently limited by the inability to provide an adequate drug concentration in blood circulation for a long term. As a promising way to overcome this problem, the long-acting forms of these drugs have attracted many interests in recent years. I...

Further mulinane diterpenoids from Azorella compacta
submitted by dacrhio13 33 minutes ago - Topic: Health
The chemical study of a dichloromethane extract from Azorella compacta was directed to the isolation of characteristic mulinane and azorellane diterpenoids in order to determine their gastroprotective activity. Usual chromatographic techniques on the extract led to the isolation of 12 compounds, ...

Structure-dependent inhibitory effects of synthetic cannabinoids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and skin tumour promotion in mice
submitted by dacrhio13 33 minutes ago - Topic: Health
Whether and how synthetic cannabinoids affect inflammation and carcinogenesis has not been well studied. The present study was thus conducted to assess effects of synthetic cannabinoids on inflammation and carcinogenesis in vivo in mice. Twenty-three analogues of synthetic cannabinoids were isola...

Prostaglandin E1-containing nanoparticles improve walking activity in an experimental rat model of intermittent claudication
submitted by dacrhio13 33 minutes ago - Topic: Health
Due to the low stability of lipid emulsions, a lipid emulsion of prostaglandin E1 (Lipo-PGE1) necessitates daily intravenous drip infusions. To overcome this issue, we developed nanoparticles containing PGE1 (Nano-PGE1). Nano-PGE1 showed a good sustained-release profile of PGE1 from the nanoparti...

Non-invasive imaging modalities for the diagnosis of coronary artery disease: The present and the future
submitted by balo9974alo 33 minutes ago - Topic: Health
The prevalence and economic burden of coronary artery disease are high. New noninvasive diagnostic imaging methods have evolved in recent decades, including coronary computed tomography angiography and cardiac magnetic resonance angiography. Investigations into functional ischemic parameters have...

The fallopian tube is the culprit and an accomplice in type II ovarian cancer: A review
submitted by balo9974alo 33 minutes ago - Topic: Health
Ovarian cancer is the most lethal gynecologic malignancy in the world. The origin or the pathogenesis of epithelial ovarian cancer is poorly understood, which often leads to failure of early detection. Development of a new approach to reduce mortality is urgent. The fallopian tubes were once seen...

Experimental Diet-Induced Atherosclerosis in Quaker Parrots (Myiopsitta monachus)
submitted by onni 35 minutes ago - Topic: Health
Spontaneous atherosclerosis is common in psittaciformes, and clinical signs associated with flow-limiting stenosis are encountered in pet birds. Nevertheless, a psittacine model of atherosclerosis has not been developed for research investigations. Sixteen captive-bred Quaker parrots (Myiopsitta ...

Personality and risk of Alzheimer's disease: New data and meta-analysis
submitted by fvw64 36 minutes ago - Topic: Health
We examine whether broad factors and specific facets of personality are associated with increased risk of incident Alzheimer's disease (AD) in a long-run longitudinal study and a meta-analysis of published studies. Participants (n = 1671) were monitored for up to 22 years from a baseline personal...




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