Biology Agriculture Aquaculture Horticulture Postharvest Forestry Geography Environment Health





View All

The role of gap junction proteins in the development of neural network functional topology
submitted by gellisy 42 minutes ago - Topic: Biology
Gap junctions (GJs) provide a common form of intercellular communication in most animal cells and tissues, from Hydra to human, including electrical synaptic signalling. Cell coupling via GJs has an important role in development in general, and in neural network development in particular. However...



Dolore ridotto con stimolazione elettrica corteccia
submitted by sarish 43 minutes ago - Topic: Health
MILANO - Ridurre il dolore con la stimolazione elettrica della corteccia motoria è possibile. Lo rivela uno studio pilota dell’Università di Milano Bicocca pubblicato sulla rivista Pain. L’effetto è indotto dalle correnti elettriche anodiche a bassa intensità che attivano una sorta di "ci...

Therapeutic effect of prolonged treatment with topical dorzolamide for cystoid macular oedema in patients with retinitis pigmentosa
submitted by oyb119 44 minutes ago - Topic: Health
AimTo evaluate the therapeutic effect of continuous treatment with topical dorzolamide (a carbonic anhydrase inhibitor) for cystoid macular oedema (CME) associated with retinitis pigmentosa (RP). 18 eyes in 10 patients with CME secondary to RP were included. Baseline visual acuity, visual field a...

Globalizing knowledge: how technological openness affects output, spatial inequality, and welfare levels
submitted by dena 46 minutes ago - Topic: Geography
Using an analytically solvable model, we study how the spatial distribution of economic activities and the ensuing welfare levels are affected by pecuniary externalities, depending on transportation costs, and localized technological externalities, due to the cost saving effect of intra- and inte...

Willingness to pay and benefit–cost analysis of modern contraceptives in Nigeria
submitted by 87hony 46 minutes ago - Topic: Health
To determine the willingness to pay (WTP) and the benefit–cost of modern contraceptives delivered through the public sector in Nigeria. Data were collected from 4517 randomly selected households. The WTP for the 6 major contraceptive methods available in the public sector was elicited. Logistic...



Real-time amplification of glyceraldehyde-3-phosphate dehydrogenase gene for quality control of leukopoor platelets
submitted by orviswopnel 47 minutes ago - Topic: Health
Leukoreduction of blood products is crucial to prevent white blood cell (WBC)-associated complications during transfusion. Of the widely accepted methods for quantifying WBCs in blood components, Nageotte hemocytometry is time-consuming and laborious whereas a specialized instrument is required f...

Nitroprusside inhibits calcium-induced impairment of red blood cell deformability
submitted by orviswopnel 47 minutes ago - Topic: Health
Red blood cell (RBC) deformation is critical for microvascular perfusion and oxygen delivery to tissues. Abnormalities in RBC deformability have been observed in aging, sickle cell disease, diabetes, and preeclampsia. Although nitric oxide (NO) prevents decreases in RBC deformability, the underly...

Factors affecting successful mobilization with plerixafor: an Italian prospective survey in 215 patients with multiple myeloma and lymphoma
submitted by orviswopnel 47 minutes ago - Topic: Health
Although the efficacy of plerixafor in peripheral blood stem cell (PBSC) mobilization has been explored in several studies, factors associated with successful plerixafor mobilization after administration of granulocyte–colony-stimulating factor (G-CSF), with or without chemotherapy, have not be...

Assessment of Toxic Metals and Phthalates in Children’s Toys and Clays
submitted by erson 51 minutes ago - Topic: Environment
Toxic metals and phthalates are introduced in the manufacturing of plastic toys and modeling clays. In Lebanon, inexpensive plastic toys and modeling clays (sold in dollar stores) are affordable and popular, and there is no legislation to monitor or regulate such toys. This study aimed to assess ...

Nrf2 activation: A potential strategy for the prevention of acute mountain sickness
submitted by geriishkoyyar 53 minutes ago - Topic: Health
Reactive oxygen species (ROS) formed during acute high altitude exposure contribute to cerebral vascular leak and development of acute mountain sickness (AMS). Nuclear factor (erythroid-derived 2)-related factor 2 (Nrf2) is a transcription factor that regulates expression of greater than 90% of a...

Reductive stress in young healthy individuals at risk of Alzheimer disease
submitted by geriishkoyyar 53 minutes ago - Topic: Health
Oxidative stress is a hallmark of Alzheimer disease (AD) but this has not been studied in young healthy persons at risk of the disease. Carrying an Apo ε4 allele is the major genetic risk factor for AD. We have observed that lymphocytes from young, healthy persons carrying at least one Apo ε4 a...

Assessment of macrophage migration inhibitory factor in humans: protocol for accurate and reproducible levels
submitted by geriishkoyyar 53 minutes ago - Topic: Health
The analytical validation of a possible biomarker is the first step in the long translational process from basic science to clinical routine. Although the chemokine-like cytokine macrophage migration inhibitory factor (MIF) has been investigated intensively in experimental approaches to various d...

Translocation of iron from lysosomes to mitochondria during ischemia predisposes to injury after reperfusion in rat hepatocytes
submitted by geriishkoyyar 53 minutes ago - Topic: Health
The mitochondrial permeability transition (MPT) initiated by reactive oxygen species (ROS) plays an essential role in ischemia–reperfusion (IR) injury. Iron is a critical catalyst for ROS formation, and intracellular chelatable iron promotes oxidative injury-induced and MPT-dependent cell death...

Oxidative damage and cellular defense mechanisms in sea urchin models of aging
submitted by geriishkoyyar 53 minutes ago - Topic: Health
The free radical, or oxidative stress, theory of aging proposes that the accumulation of oxidative cellular damage is a major contributor to the aging process and a key determinant of species longevity. This study investigates the oxidative stress theory in a novel model for aging research, the s...

Secondary primary cancer in patients with head and neck carcinoma: the differences among hypopharyngeal, laryngeal, and other sites of head and neck cancer
submitted by moysen 53 minutes ago - Topic: Health
This paper presents a population-based retrospective cohort study to identify the differences in secondary primary cancer (SPC) among hypopharyngeal, laryngeal, and other sites of head and neck cancer (HNC). Data were collected from the Taiwan National Health Insurance Research Database (NHIRD) f...