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AgTrend: A Bayesian Approach for Estimating Trends of Aggregated Abundance
submitted by sodighepaar 14 minutes ago - Topic: Biology
1. We describe a method and open source R package agTrend for analyzing regional trends of abundance from sites with uneven sample schedules over space and time.2. The method uses a hierarchical model to augment missing abundance measurements, while accounting for survey methodology changes and variability due to survey replication. A zero-inated log-normal distribution is used to model abundan...



Imputation of missing data in life-history traits datasets: which approach performs the best?
submitted by sodighepaar 14 minutes ago - Topic: Biology
1. Despite efforts in data collection, missing values are commonplace in life-history trait databases. Because these values typically are not missing randomly, the common practice of removing missing data not only reduces sample size, but also introduces bias that can lead to incorrect conclusions. Imputing missing values is a potential solution to this problem. Here, we evaluate the performanc...

Transmitting species-interaction data from animal–borne transceivers through Service Argos using Bluetooth communication
submitted by sodighepaar 14 minutes ago - Topic: Biology
Interactions between upper trophic level predators and their prey remain poorly understood due to their inaccessibility during foraging at sea. This uncertainty has fuelled debate on the impact of predation by species such as the grey seal (Halichoerus grypus) on fish stocks. The Vemco Mobile Transceiver (VMT) has provided us with new knowledge on interactions between pinnipeds and fish species...

Treatment of urological complications in more than 1,000 kidney transplantations: the role of interventional radiology
submitted by ivintari 16 minutes ago - Topic: Health
The aim of this study is to evaluate the efficacy and safety of interventional radiology procedures in the treatment of major urological complications after kidney transplantation. Between 2000 and 2010, 1,146 kidney transplants were performed at our institution. A total of 146 major complications occurred, including 77 obstructions, 36 leaks and 33 associated perigraft fluid collections. Percu...

Cardiac MR perfusion imaging: where we are
submitted by ivintari 16 minutes ago - Topic: Health
To date, several clinical and multicentre studies have demonstrated the accuracy of perfusion cardiac magnetic resonance to detect ischaemia in comparison with quantitative coronary angiography, other noninvasive diagnostic techniques (single photon emission computed tomography; positron-emission tomography), and invasive haemodynamic measurements (fractional flow reserve). Moreover, the favour...



The role of interventional radiology in the treatment of biliary strictures after paediatric liver transplantation
submitted by ivintari 16 minutes ago - Topic: Health
The aim of this study is to evaluate the safety and efficacy of percutaneous treatment of biliary strictures after paediatric liver transplantation. In the period between October 1999 and October 2010, a total of 92 transplants in 86 children were performed at our Liver Transplant Centre. Eighteen patients had anastomotic biliary strictures (in four cases associated with intrahepatic bile duct ...

Parotid glands in whole-brain radiotherapy: 2D versus 3D technique for no sparing or sparing
submitted by ivintari 16 minutes ago - Topic: Health
Whole-brain radiotherapy is performed as standard therapy in patients with multiple brain metastases and in patients with more favourable prognosis such as lymphoma and small-cell lung carcinoma in the prophylactic setting. Because of the prognosis and the total prescribed dose, the parotid glands are not usually regarded as an organ at risk in whole-brain radiotherapy. Long-term survival can b...


Percutaneous segmental dilatation of portal stenosis after paediatric liver transplantation to avoid or postpone surgery: two cases and literature review
submitted by ivintari 16 minutes ago - Topic: Health
The authors retrospectively reviewed the results obtained with percutaneous treatment of portal stenosis. In November 2005 and March 2008, two patients, 15 and 32 months old, underwent portal vein angioplasty at our centre. Both procedures were performed after ultrasound-guided portal vein puncture and measurement of pre- and postanastomotic pressure gradients. The diameters of the angioplasty...

Orbital Stem Cells
submitted by ntgrzych 31 minutes ago - Topic: Health
Stem cell research in the field of ophthalmology over the past two decades has advanced knowledge and treatment dramatically. Bone marrow-derived stem cells (BM-MSCs) have been widely studied and have many applications in the eye and other organs; since processed lipoaspirate was first identified as a source of adipose tissue derived stem cells (ASCs), further research has blossomed in this exc...


Regulatory framework of pharmaceutical compounding and actual developments of legislation in Europe
submitted by glniwtan 33 minutes ago - Topic: Health
Pharmaceutical preparations are medicines that the pharmacist makes for the special needs of the patients that the pharmaceutical industry can’t comply for economic and logistic reasons. Pharmacy compounding is still an important component of pharmacy practice and a valuable therapeutical service that is an integrant part of the modern health care system, but its legislation is not harmonized...

Improved estimates of Belgian private health expenditure can give important lessons to other OECD countries
submitted by glniwtan 33 minutes ago - Topic: Health
Oecd Health Data are a well-known source for detailed information about health expenditure. These data enable us to analyse health policy issues over time and in comparison with other countries. However, current official Belgian estimates of private expenditure (as published in the oecd Health Data) have proven not to be reliable. We distinguish four potential major sources of problems with est...


Druggists and pharmacists as gatekeepers: Sales routines and compliance with sales protocols for over-the-counter naproxen 275mg medicines in the Netherlands
submitted by glniwtan 34 minutes ago - Topic: Health
Since for over-the-counter (OTC) medicines no prescribing physicians are involved and written instructions on/in the medicine boxes are inefficient, druggists and pharmacists are important gatekeepers in preventing customers’ accidents. In this study we investigated the sales routines, and compliance with sales protocols, in order to evaluate that gatekeeper's function. By means of the myster...

The Effect of Physician Supply on Health Status: Canadian Evidence
submitted by glniwtan 34 minutes ago - Topic: Health
We estimate the relationship between per capita supply of physicians, both general practitioners and specialists, and health status of Canadians. We use data from the Canadian National Population Health Survey and the Canadian Institute for Health Information. Two measures of quality of life, self-assessed health status and the Health Utility Index, are explored. Random effects ordered probits ...

Substrate Stiffness Mediated Metastasis Like Phenotype of Colon Cancer Cells is Independent of Cell to Gel Adhesion
submitted by bolzonmv 35 minutes ago - Topic: Biology
Growing experimental evidences suggest that cells can feel and respond to the mechanical stiffness of the substrate on which they adhere. Human colon carcinoma (HCT-8) cells can exhibit a dissociative, metastasis-like phenotype (MLP) in vitro when cultured on extra-cellular matrix (ECM) coated polyacrylamide (PA) hydrogels with appropriate mechanical stiffness (20–47 kPa), but not on very st...

Efficiency of Protease-Activatable Virus Nanonodes Tuned Through Incorporation of Wild-Type Capsid Subunits
submitted by bolzonmv 35 minutes ago - Topic: Biology
Virus nanonodes, a tunable multi-input protease-responsive gene delivery platform, was recently built by exploiting the self-assembly property of adeno-associated virus capsids. Upon detection of specific inputs (e.g., matrix metalloproteinases—MMPs), the engineered viruses output gene delivery to targeted cells. The first generation protease-activatable viruses (PAVs) displayed the desired p...