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Development of targeted messages to promote smoking cessation among construction trade workers
submitted by zopotireos 24 minutes ago - Topic: Health
Blue-collar workers, particularly those in the construction trades, are more likely to smoke and have less success in quitting when compared with white-collar workers. Little is known about health communication strategies that might influence this priority population. This article describes our formative work to develop targeted messages to increase participation in an existing smoking cessatio...



Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood
submitted by onni 27 minutes ago - Topic: Health
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by the progressive loss of motor neurons within the central nervous system. Neural degeneration and inflammatory processes, including activation of the complement system are hallmarks of this pathology. Our past work in ALS animal models (hSOD1G93A rodents) has revealed that blockade of the receptor for comp...

Effects of ouabain on cytokine/chemokines levels in an animal model of mania
submitted by onni 27 minutes ago - Topic: Health
Bipolar disorder (BD) is a chronic and severe psychiatric disorder and despite its importance, little is known about the precise pathophysiology of this disorder. Several studies have reported that inflammation plays a role in the pathogenesis of BD and that cytokines are altered in these patients. Intracerebroventricular (ICV) injection of ouabain (a potent Na+/K+-ATPase inhibitor) in rats res...

Grey matter damage in progressive multiple sclerosis versus amyotrophic lateral sclerosis: a voxel-based morphometry MRI study
submitted by onceint3434 32 minutes ago - Topic: Health
Primary progressive multiple sclerosis (PPMS) and amyotrophic lateral sclerosis (ALS) seem to share some clinical and pathological features. MRI studies revealed the presence of grey matter (GM) atrophy in both diseases, but no comparative data are available. The objective was to compare the regional patterns of GM tissue loss in PPMS and ALS with voxel-based morphometry (VBM). Eighteen PPMS pa...

Clinical features of drug-induced parkinsonism based on [18F] FP-CIT positron emission tomography
submitted by onceint3434 32 minutes ago - Topic: Health
Drug-induced parkinsonism (DIP) is the common cause of parkinsonism. It is difficult to make a differentiation between DIP and Parkinson’s disease (PD) because there are no notable differences in the clinical characteristics between the two entities. In this study, we examined the relationship between the characteristics of [18F] fluorinated-N-3-fluoropropyl-2-β-carboxymethoxy-3-β-(4-iodoph...



Identifying the role of microRNAs in spinal cord injury
submitted by onceint3434 32 minutes ago - Topic: Health
Spinal cord injury (SCI) is medically and socioeconomically debilitating, and effective treatments are lacking. The elucidation of the pathophysiological mechanisms underlying SCI is essential for developing effective treatments for SCI. MicroRNAs (miRNAs) are small non-coding RNA molecules (18–24 nucleotides long) that regulate gene expression by interacting with specific target sequences. R...

Site-level model intercomparison of high latitude and high altitude soil thermal dynamics in tundra and barren landscapes
submitted by ijo 43 minutes ago - Topic: Geography
Modelling soil thermal dynamics at high latitudes and altitudes requires representations of specific physical processes such as snow insulation, soil freezing/thawing, as well as subsurface conditions like soil water/ice content and soil texture type. We have compared six different land models (JSBACH, ORCHIDEE, JULES, COUP, HYBRID8, LPJ-GUESS) at four different sites with distinct cold region ...


Subchondral insufficiency fractures and spontaneous osteonecrosis of the knee may not be related to osteoporosis
submitted by moenasdeas 43 minutes ago - Topic: Health
The term insufficiency fracture implies inadequate bone and is applied to some subchondral knee magnetic resonance images. We reviewed bone mineral density, body mass index, meniscal extrusion, comorbidities, and demographics in 32 knee insufficiency fracture patients. Only five were osteoporotic. Meniscal extrusion was predominant. The literature supports systemic osteoporosis as a risk fractu...

Dark Matter in the minimal Inverse Seesaw mechanism
submitted by hetz2333 43 minutes ago - Topic: Geography
We consider the possibility of simultaneously addressing the dark matterproblem and neutrino mass generation in the minimal inverse seesaw realisation. The Standard Model is extended by two right-handed neutrinos and three sterilefermionic states, leading to three light active neutrino mass eigenstates, twopairs of (heavy) pseudo-Dirac mass eigenstates and one (mostly) sterile statewith mass ar...


Depth of Maximum of Air-Shower Profiles at the Pierre Auger Observatory: Composition Implications
submitted by hetz2333 43 minutes ago - Topic: Geography
Using the data taken at the Pierre Auger Observatory between December 2004and December 2012, we have examined the implications of the distributions ofdepths of atmospheric shower maximum (Xmax), using a hybrid technique, forcomposition and hadronic interaction models. We do this by fitting thedistributions with predictions from a variety of hadronic interaction modelsfor variations in the compo...

Spectral properties of the largest asteroids associated with Taurid Complex
submitted by hetz2333 43 minutes ago - Topic: Geography
We obtained spectra of six of the largest asteroids (2201, 4183, 4486, 5143,6063, and 269690) associated with Taurid complex. The observations were madewith the IRTF telescope equipped with the spectro-imager SpeX. Their taxonomicclassification is made using Bus-DeMeo taxonomy. The asteroid spectra arecompared with the meteorite spectra from the Relab database. Mineralogicalmodels were applied ...


Atmospheric Circulation of Eccentric Hot Jupiter HAT-P-2b
submitted by hetz2333 43 minutes ago - Topic: Geography
The hot-Jupiter HAT-P-2b has become a prime target for Spitzer SpaceTelescope observations aimed at understanding the atmospheric response ofexoplanets on highly eccentric orbits. Here we present a suite ofthree-dimensional atmospheric circulation models for HAT-P-2b that investigatethe effects of assumed atmospheric composition and rotation rate on globalscale winds and thermal patterns. We co...

Depolarization of multiple scattered light in atmospheres due to anisotropy of small grains and molecules. II. The problems with sources
submitted by hetz2333 43 minutes ago - Topic: Geography
In the previous paper we considered two classic problems - the diffusereflection of the light beam from semi-infinite atmosphere, and the Milneproblem. For both problems we used the technique of invariance principle. Inthis paper we consider the solution of the problem when in semi-infiniteatmosphere the sources of unpolarized radiation are exist. Here we used thetechnique of the Green matrices...

An Estimate of the Spectral Intensity Expected from the Molecular Bremsstrahlung Radiation in Extensive Air Showers
submitted by hetz2333 43 minutes ago - Topic: Geography
A detection technique of ultra-high energy cosmic rays, complementary to thefluorescence technique, would be the use of the molecular Bremsstrahlungradiation emitted by low-energy electrons left after the passage of the showersin the atmosphere. The emission mechanism is expected from quasi-elasticcollisions of electrons produced in the shower by the ionisation of themolecules in the atmosphere...

Radial dependence of line profile variability in seven O9--B0.5 stars
submitted by hetz2333 43 minutes ago - Topic: Geography
Massive stars show a variety of spectral variability: presence of discreteabsorption components in UV P-Cygni profiles, optical line profile variability,X-ray variability, radial velocity modulations. Our goal is to study thespectral variability of single OB stars to better understand the relationbetween photospheric and wind variability. For that, we rely on high spectralresolution, high signa...