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Risk factors and survival outcomes in patients with brain metastases from breast cancer
submitted by phainex 23 minutes ago - Topic: Health
Development of central nervous system (CNS) metastases in breast cancer (BC) is associated with poor prognosis. The incidence of CNS metastases in metastatic BC is reported to be about 10–16 %, but different subtypes of BC are associated with different risk of developing CNS metastases. We ret...



MicroRNAs in domestic livestock
submitted by goleles 23 minutes ago - Topic: Biology
MicroRNAs (miRNAs) are a class of small non-coding RNA that bind to complementary sequences in the untranslated regions of multiple target mRNAs resulting in posttranscriptional regulation of gene expression. The recent discovery and expression- profiling studies of miRNAs in domestic livestock h...

Wave-ice interactions in the marginal ice zone. Part 1: Theoretical foundations
submitted by tatabolodo 28 minutes ago - Topic: Geography
A wave-ice interaction model for the marginal ice zone (MIZ) is reported that calculates the attenuation of ocean surface waves by sea ice and the concomitant breaking of the ice into smaller floes by the waves. Physical issues are highlighted that must be considered when ice breakage and wave at...

L1CAM in Early-Stage Type I Endometrial Cancer: Results of a Large Multicenter Evaluation
submitted by xpta 29 minutes ago - Topic: Health
Despite the excellent prognosis of Fédération Internationale de Gynécologie et d’Obstétrique (FIGO) stage I, type I endometrial cancers, a substantial number of patients experience recurrence and die from this disease. We analyzed the value of immunohistochemical...

Managing to Low-Density Lipoprotein Particles Compared to Low-Density Lipoprotein Cholesterol: A Cost-Effective Analysis
submitted by rozon44 30 minutes ago - Topic: Health
Meta-analyses of clinical trials have shown that using statins to lower low-density lipoprotein cholesterol (LDL-C) reduces cardiovascular events,and more intensive lowering of LDL-C further decreases the risk of occlusive vascular events. Lipoprotein studies suggest treating patients more aggres...



Lipid control in patients with coronary heart disease treated in primary care or cardiology clinics
submitted by rozon44 30 minutes ago - Topic: Health
Guidelines recommend low-density lipoprotein-cholesterol (LDL-C) target of <70 mg/dl in patients with coronary disease. However, this goal is not achieved in many patients. To compare LDL-C control in patients with coronary disease treated by a primary care physician or with the addition o...

Treatment Pattern Changes in High-Risk Patients Newly Initiated on Statin Monotherapy in a Managed Care Setting
submitted by rozon44 30 minutes ago - Topic: Health
To determine treatment pattern changes among patients with high-risk for CVD who were not at LDL-C goal on statin monotherapy. Treatment pattern changes were evaluated among patients newly initiated on statins between 1/1/2006-8/31/2009 in the HealthCore Integrated Research Database. Rates and me...

Increased Incidence of Dog-Bite Injuries after the Fukushima Nuclear Accident
submitted by soltcido 31 minutes ago - Topic: Health
To assess the localized incidence of dog bites following the nuclear accident related to the Great East Japan Earthquake in March 2011. We identified the patients with dog bites in our hospital in Minamisoma City, Fukushima, during the period from 1 year prior to the earthquake to 3.5 months foll...

Performance of light-emitting diode fluorescence microscope for diagnosis of tuberculosis
submitted by stiphinhjocabsan 32 minutes ago - Topic: Biology
Fluorescence microscopy (FM) over the years has shown the potential for increasing the performance of microscopy. The present study was aimed to access the performance of the LED microscope for the detection of acid fast bacilli in a tuberculosis (TB) endemic country. The study was conducted at a...

Nyamulagira's magma plumbing system inferred from 15 years of InSAR
submitted by ondriries00 33 minutes ago - Topic: Geography
Nyamulagira, located in the east of the Democratic Republic of Congo on the western branch of the East African rift, is Africa’s most active volcano, with an average of one eruption every 3 years since 1938. Owing to the socio-economical context of that region, the volcano lacks ground-base...

Anatectic reworking and differentiation of continental crust along the active margin of Gondwana: a zircon Hf-O perspective from West Antarctica
submitted by ondriries00 33 minutes ago - Topic: Geography
The Fosdick migmatite–granite complex of West Antarctica preserves evidence of two crustal differentiation events along a segment of the former active margin of Gondwana, one in the Devonian–Carboniferous and another in the Cretaceous. The Hf–O isotope composition of zircons fro...

Basin compartmentalization and drainage evolution during rift inversion: evidence from the Eastern Cordillera of Colombia
submitted by ondriries00 33 minutes ago - Topic: Geography
The Cenozoic stratigraphic infill of hinterland and foreland basins in central Colombia holds the record of basin development during tectonic inversion of rift in the context of subduction orogenesis. A comprehensive review of detrital U–Pb geochronologic and thermochronologic data reveals ...

Shortening, structural relief and drainage evolution in inverted rifts: insights from the Atlas Mountains, the Eastern Cordillera of Colombia and the Pyrenees
submitted by ondriries00 33 minutes ago - Topic: Geography
The Atlas, Eastern Cordillera and Pyrenees are thick-skinned thrust-fold belts formed by tectonic inversion of rift basins in continental settings. A comparison of shortening between them shows a gradation from 20–25% in the central High Atlas, to 25–30% in the Eastern Cordillera, and...

Innovation in Technology-Aided Psychotherapy Through Human Factors/Ergonomics: Toward a Collaborative Approach
submitted by megailprainco 34 minutes ago - Topic: Health
Technologies are being used increasingly to aid psychotherapy and are becoming an integral part of mental health treatment. Although prior studies compared technology-aided psychotherapy (TAP) to traditional treatments, there are insufficient studies of the impact that specific design parameters ...

Multiplicity of Effectors of the Cardioprotective Agent, Diazoxide
submitted by ono 35 minutes ago - Topic: Health
Diazoxide has been identified over the past 50 years to have a number of physiological effects, including lowering the blood pressure and rectifying hypoglycemia. Today it is used clinically to treat these conditions. More recently, another important mode of action emerged: diazoxide has powerful...